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Tests and diagnosis
By Mayo Clinic staffTo diagnose botulism, your doctor will check you for signs of muscle weakness or paralysis, such as drooping eyelids and a weak voice. Your doctor will also ask about the foods you've eaten in the past few days, and ask if you may have been exposed to the bacteria through a wound. A blood test can confirm the presence of the toxin.
In cases of possible infant botulism, the doctor may ask if the child has eaten honey recently and has had problems such as constipation and sluggishness.
Analysis of stool or vomit for evidence of the toxin may help confirm an infant or food-borne botulism diagnosis, but because these tests may take days, your doctor's clinical examination is the primary means of diagnosis.
- Pegram PS, et al. Botulism. http://www.uptodate.com/home/index.html. Accessed Jan. 29, 2010.
- Botulism. Centers for Disease Control and Prevention. http://www.cdc.gov/nczved/dfbmd/disease_listing/botulism_gi.html. Accessed Feb. 4, 2010.
- Botulism. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec14/ch178/ch178c.html. Accessed Feb. 3, 2010.
- Sobel J. Botulism. Clinical Infectious Diseases. 2005;41:1167.
- Abrutyn E. Botulism. In: Fauci AS, et al. Harrison's Principles of Internal Medicine. 17th ed. New York, N.Y.: McGraw-Hill Medical; 2008. http://www.accessmedicine.com/content.aspx?aID=2867436. Accessed Feb. 3, 2010.
- Follow-up to the February 8, 2008, early communication about an ongoing safety review of Botox and Botox Cosmetic (Botulinum toxin Type A) and Myobloc (Botulinum toxin Type B). U.S. Food and Drug Administration. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/ucm143819.htm. Accessed Feb. 5, 2010.
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