Brain lesions

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Definition

By Mayo Clinic staff

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MRI showing a brain lesion 
MRI showing a brain lesion

Brain lesions are abnormal areas of tissue in your brain. Most likely, you've learned that you have a brain lesion or brain lesions as an incidental finding after having a brain-imaging test — such as magnetic resonance imaging (MRI) or a computerized tomography (CT) scan — performed for some reason. On MRI images, for example, brain lesions appear as dark or light spots that don't look like normal brain tissue.

If you've been diagnosed with something described as a brain lesion, it implies that the cause of the abnormal-appearing area cannot be diagnosed by the image alone, and further evaluation is necessary.

A brain lesion may involve small to large areas of your brain, and the severity of the underlying condition may range from relatively minor to life-threatening.

References
  1. Morris Z, et al. Incidental findings on brain magnetic resonance imaging: Systematic review and meta-analysis. British Medical Journal. 2009;339:b3016.
  2. Papanikolaou V, et al. Incidental findings on MRI scans of patients presenting with audiovestibular symptoms. BMC Ear, Nose and Throat Disorders. 2010;10:6.
  3. NINDS acute disseminated encephalitis information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/acute_encephalomyelitis/acute_encephalomyelitis.htm. Accessed Aug. 15, 2011.
  4. Ropper AH, et al. Disturbances of cerebrospinal fluid and its circulation, including hydrocephalus, pseudotumor cerebri, and low-pressure syndromes. In: Ropper AH, et al. Adams & Victor's Principles of Neurology. 9th ed. New York, N.Y.: The McGraw-Hill Companies; 2009. http://www.accessmedicine.com/content.aspx?aID=3635132&searchStr=hydrocephalus#3635132. Accessed Aug. 15, 2011.
  5. Waxman SG. The relationship between neuroanatomy and neurology. In: Waxman SG. Clinical Neuroanatomy. 26th ed. New York, NY.:The McGraw-Hill Companies. 2010. http://www.accessmedicine.com/content.aspx?aid=5271560. Accessed Aug. 13, 2011.
  6. Wong ET, et al. Clinical presentation and diagnosis of brain tumors. http://www.uptodate.com/home/index.html. Accessed Aug. 13, 2011.
  7. Oliveira-Filho J, et al. Neuroimaging of acute ischemic stroke. http://www.uptodate.com/home/index.html. Accessed Aug. 13, 2011.
  8. Wilkinson JM (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 15, 2011.
MY00847 Oct. 25, 2011

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