Adjuvant therapy guide for breast cancer

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Radiation therapy for breast cancer

By Mayo Clinic staff

Radiation therapy uses high-powered X-rays to kill cancer cells, decreasing the risk of cancer recurrence. Radiation therapy is almost always recommended after lumpectomy, and it's sometimes recommended for high-risk women following mastectomy.

Your doctor may recommend radiation therapy if you have:

  • A wide local excision (lumpectomy)
  • A tumor larger than 5 centimeters (about 2 inches)
  • Tumor growth into the chest muscles
  • Multiple lymph nodes that test positive for cancer
  • Inflammatory breast cancer

One of two different approaches may be used:

  • External radiation. External beam radiation, the standard type of radiation therapy, delivers radiation to your breast from a machine outside your body.
  • Internal radiation. Internal radiation, or brachytherapy, uses tiny, implantable radioactive devices ("seeds") placed in your breast near the tumor site to deliver radiation to affected breast tissue.

Radiation therapy usually begins about three to six weeks after surgery. If you choose chemotherapy and radiation as adjuvant therapy, you usually receive chemotherapy first, followed by the radiation. Radiation therapy can be done at the same time as adjuvant hormone therapy. The risk of breast cancer recurrence is no different if you choose lumpectomy with radiation or mastectomy without radiation.

Side effects of radiation therapy
Radiation therapy is a cumulative process, and its side effects tend to become more of an issue as time passes.

Common side effects include:

  • Mild to moderate fatigue
  • Skin irritation — such as itchiness, redness, peeling or blistering — similar to what you might experience with a sunburn
  • Breast swelling
  • Changes in skin sensation

Rarely, radiation therapy may cause:

  • Arm swelling (lymphedema)
  • Rib tenderness
  • Inflamed lung tissue
  • Heart damage
  • Secondary cancers

Some breast changes may be permanent after radiation. These include changes in skin color, feelings of heaviness in your breast, changes in the texture of your breast and even size changes.

Radiation therapy for breast cancer: Pros and cons Chemotherapy: Pros and cons

MY00199

Aug. 5, 2008

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