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Breast cysts: What role does caffeine play?

By Mayo Clinic staff

Original Article:  http://www.mayoclinic.com/health/breast-cysts/AN00889
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  • With Mayo Clinic internist

    Sandhya Pruthi, M.D.

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Question

Breast cysts: What role does caffeine play?

Does caffeine cause breast cysts?

Answer

from Sandhya Pruthi, M.D.

No, caffeine doesn't appear to cause breast cysts (fibrocystic breast changes), a noncancerous (benign) breast disease. In large quantities, though, caffeine can raise the levels of cortisol and other stress hormones in your system — and stress hormones may, over time, affect your reproductive hormones. The interplay of caffeine, stress hormones and reproductive hormones could play a role in premenstrual breast swelling and discomfort.

Anecdotally, some women report reduced breast pain when they go off caffeine. Although no research has documented this effect, there's no reason not to go caffeine-free to see if it relieves discomfort from breast cysts.

Also, if you drink several cups of coffee on a typical day, you might consider cutting back. Data from two large, long-term women's health studies suggest a connection between high caffeine intake and precancerous or high-risk breast lesions.

Next question
Fibrocystic breast changes: Linked to breast cancer?
References
  1. Rosolowich V, et al. Mastaglia: SOGC Clinical Practice Guideline 170. Journal of Obstetrics and Gynaecology Canada. 2006;28:49.
  2. Webb P, et al. A prospective study of diet and benign breast disease. Cancer Epidemiology, Biomarkers and Prevention. 2004;13:1106.
  3. Ishitani K, et al. Caffeine consumption and the risk of breast cancer in a large prospective cohort of women. Archives of Internal Medicine. 2008;168:2022. http://archinte.ama-assn.org/cgi/content/full/168/18/2022. Accessed Nov. 8, 2010.
  4. Harris A, et al. Coffee, stress and cortisol in nursing staff. Psychoneuroendocrinology. 2007;2:322.
  5. Kajantie E, et al. The effects of sex and hormonal status on the physiological response to acute psychosocial stress. Psychoneuroendocrinology. 2006;31:151.
  6. Diagnosis of breast disease. Bloomington, Minn.: Institute for Clinical Systems Improvement. http://www.icsi.org/breast_disease_diagnosis/diagnosis_of_breast_disease_2.html. Accessed Nov. 4, 2010.
AN00889 Nov. 16, 2010

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