Bullous pemphigoid

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Complications

By Mayo Clinic staff

Serious complications of bullous pemphigoid are more likely in older adults and in those in generally poor health. These include:

  • Infections at the site of ruptured blisters
  • Widespread infection in other tissues (sepsis)

Depending on the severity and location of blisters, bullous pemphigoid may disrupt typical activities of daily living. The blisters and itching may make it difficult to:

  • Maintain personal hygiene
  • Wear certain clothing or shoes comfortably
  • Eat or drink if blisters or sores are in the mouth
  • Sleep comfortably

A person may also be self-conscious or embarrassed by his or her appearance. All of these complications can affect a person's health, social interactions, physical activity and general well-being.

References
  1. Bullous pemphigoid. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec10/ch112/ch112b.html. Accessed April 21, 2010.
  2. Goldstein BG, et al. Bullous pemphigoid and other pemphigoid disorders. http://uptodate.com/home/index.html. Accessed April 15, 2010.
  3. Stanley J. Bullous pemphigoid. In: Wolff K, et al., eds. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: McGraw-Hill Medical; 2008. http://www.accessmedicine.com/content.aspx?aID=2950538. Accessed April 21, 2010.
  4. Kirtschig G, et al. Management of bullous pemphigoid: Recommendations for immunomodulatory treatments. American Journal of Clinical Dermatology. 2004;5:319.
  5. Patton T, et al. Bullous pemphigoid treatment review. Expert Opinion in Pharmacotherapy. 2006;7:2403.
  6. Glucocorticosteroid-induced osteoporosis. American College of Rheumatology. http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/gi-osteoporosis.asp. Accessed April 15, 2010.
DS00722 June 10, 2010

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