Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get StartedComplications
By Mayo Clinic staffSkin infections are a common complication of bullous pemphigoid.
Other complications of bullous pemphigoid may arise from the medications used to treat the condition. Corticosteroids and drugs called immunosuppressants help treat bullous pemphigoid, but they also depress your immune system functions, which may increase your likelihood of developing certain infections and cancers. Taking corticosteroids over long periods of time may increase your risk of osteoporosis and bone fractures.
Bullous pemphigoid can also affect your quality of life. Blisters appearing in your mouth may make it more difficult for you to eat. You may find that it's tricky to complete your daily activities if you have ruptured blisters or blisters on the palms of your hands or soles of your feet. And bullous pemphigoid occurring in the eyes can lead to scarring, which could affect your vision.