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Treatments and drugs
By Mayo Clinic staffThere's no one sure way to treat primary burning mouth syndrome, and solid research on the most effective methods is lacking. Treatment depends on your particular signs and symptoms, as well as any underlying conditions that may be causing your mouth pain. That's why it's important to try to pinpoint the cause. Once any underlying causes are treated, your burning mouth syndrome symptoms should get better.
If a cause can't be found, treatment can be challenging. There's no known cure for primary burning mouth syndrome. You may need to try several treatment methods before finding one or a combination that is helpful in reducing your mouth pain. Treatment options may include:
- A lozenge-type form of the anticonvulsant medication clonazepam (Klonopin)
- Alpha-lipoic acid, a strong antioxidant produced naturally by the body
- Oral thrush medications
- Certain antidepressants
- B vitamins
- Cognitive behavioral therapy
- Specific oral rinses or mouthwashes
- Saliva replacement products
- Capsaicin, a pain reliever that comes from chili peppers
Surgery isn't recommended for burning mouth syndrome.
- Lustig LR, et al. Ear, nose & throat disorders. In: McPhee SJ, et al. Current Medical Diagnosis & Treatment 2010. 49th ed. New York, N.Y.: McGraw-Hill; 2010. http://www.accessmedicine.com/content.aspx?aID=2617&searchStr=burning+mouth+syndrome. Accessed May 10, 2010.
- Burning mouth syndrome. National Institute of Dental and Craniofacial Research. http://www.nidcr.nih.gov/OralHealth/Topics/Burning/BurningMouthSyndrome.htm. Accessed May 10, 2010.
- What is burning mouth syndrome? Academy of General Dentistry. http://www.agd.org/public/oralhealth/Default.asp?IssID=293&Topic=B&ArtID=1141#body. Accessed May 10, 2010.
- Mirowski GW, et al. Biology and pathology of the oral cavity. In: Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: McGraw-Hill; 2008. http://www.accessmedicine.com/content.aspx?aID=2979105&searchStr=glossalgia#2979105. Accessed May 10, 2010.
- Klasser GD, et al. Burning mouth syndrome: Recognition, understanding, and management. Oral Maxillofacial Surgery Clinics of North America. 2008;20:255.
- Drage LA, et al. Clinical assessment and outcome in 70 patients with complaints of burning or sore mouth symptoms. Mayo Clinic Proceedings. 1999;74:223.
- Drage LA, et al. Burning mouth syndrome. Dermatologic Clinics. 2003;21:135.
- Drage LA, et al. Burning mouth syndrome (glossodynia). In: Lebwohl MG, et al. Treatment of Skin Disease: Comprehensive Therapeutic Strategies. 3rd ed. Philadelphia, Pa.: Elsevier Health Sciences; 2010:111.
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