Complications
By Mayo Clinic staffCancer and its treatment can cause several complications, including:
- Pain. Pain can be caused by cancer or by cancer treatment. Most cancer-related pain can be treated effectively.
- Fatigue. Fatigue in people with cancer has many causes, but it can often be managed. Fatigue associated with chemotherapy or radiation therapy treatments is common, but it's usually temporary.
- Difficulty breathing. Cancer or cancer treatment may cause a feeling of being short of breath. Treatments may bring relief.
- Nausea. Certain cancers and cancer treatments can cause nausea. Your doctor can sometimes predict if your treatment is likely to cause nausea. Medications and other treatments may help you prevent or cope with nausea.
- Diarrhea or constipation. Cancer and cancer treatment can affect your bowels and cause diarrhea or constipation.
- Unusual immune system reactions to cancer. In some cases the body's immune system may react to the presence of cancer by attacking healthy cells. Called paraneoplastic syndromes, these unusual reactions can lead to a variety of signs and symptoms, such as difficulty walking and seizures.
- Cancer that spreads. As cancer advances, it may spread (metastasize) to other parts of the body. Where cancer spreads depends on the type of cancer. In general, cancer that has spread may be managed, but it can't be cured.
- Cancer that returns. Cancer survivors have a risk of cancer recurrence. Some cancers are more likely to recur than others. Ask your doctor about what you can do to reduce your risk of cancer recurrence. Your doctor may devise a follow-up care plan for you after treatment. This plan may include periodic scans and exams in the months and years after your treatment, to look for cancer recurrence.
References
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- Cancer: All sites. Surveillance Epidemiology and End Results. http://seer.cancer.gov/statfacts/html/all.html. Accessed March 12, 2010.
- What you need to know about cancer. National Cancer Institute. http://www.cancer.gov/cancertopics/wyntk/cancer/allpages. Accessed Feb. 17, 2010.
- Kleinsmith LJ, et al. Understanding cancer. National Cancer Institute. http://nci.nih.gov/cancertopics/understandingcancer/cancer. Accessed March 16, 2010.
- Fearon ER, et al. Progressing from gene mutations to cancer. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2008:207.
- Ulcerative colitis. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/colitis/index.htm. Accessed March 16, 2010.
- NINDS paraneoplastic syndromes information page. National Institute of Neurological Disorder and Stroke. http://www.ninds.nih.gov/disorders/paraneoplastic/paraneoplastic.htm. Accessed March 16, 2010.
- Mansky PJ, et al. Complementary medicine in palliative care and cancer symptoms management. Cancer Journal. 2006;12:425.
- Kushi LH, et al. American Cancer Society guidelines on nutrition and physical activity for cancer prevention: Reducing the risk of cancer with healthy food choices and physical activity. CA: A Cancer Journal for Clinicians. 2006;56:254.
- Moynihan TJ (expert opinion). Mayo Clinic, Rochester, Minn. March 18, 2010.

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