Carcinoid tumors

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Risk factors

By Mayo Clinic staff

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Factors that increase the risk of carcinoid tumors include:

  • Older age. Older adults are more likely to be diagnosed with a carcinoid tumor than are younger people or children.
  • Sex. Women are more likely than men to develop carcinoid tumors.
  • Family history. A family history of multiple endocrine neoplasia, type I (MEN I), increases the risk of carcinoid tumors. In people with MEN I, multiple tumors occur in glands of the endocrine system.
  • Smoking. Smoking tobacco may increase the risk of carcinoid tumors.
  • Other medical conditions. Conditions that affect the stomach's ability to produce acid, such as gastritis and Zollinger-Ellison syndrome, can increase your risk of gastrointestinal carcinoids.
References
  1. Kulke MH. Clinical presentation and management of carcinoid tumors. Hematology/Oncology Clinics of North America. 2007;21:433.
  2. Pasieka JL. Carcinoid tumors. Surgical Clinics of North America. 2009;89:1123.
  3. Chang BB, et al. Neuroendocrine carcinoma. In: Kantarjian HM, et al. MD Anderson Manual of Medical Oncology. New York, N.Y.: McGraw Hill; 2006. http://www.accessmedicine.com/content.aspx?aID=2790810. Accessed Aug. 6, 2010.
  4. Lung carcinoid tumor. American Cancer Society. http://www.cancer.org/acs/groups/cid/documents/webcontent/003117-pdf.pdf. Accessed Aug. 6, 2010.
  5. Scherubel H, et al. Neuroendocrine tumors of the stomach (gastric carcinoids) are on the rise: Small tumors, small problems? Endoscopy. 2010;42:664.
  6. Sitaraman SV, et al. Diagnosis of the carcinoid syndrome and tumor localization. http://www.uptodate.com/home/index.html. Accessed Aug. 3, 2010.
  7. Jensen RT. Endocrine tumors of the gastrointestinal tract and pancreas. In: Fauci AS, et al. Harrison's Principles of Internal Medicine. 17th ed. New York, N.Y.: McGraw Hill; 2008. http://www.accessmedicine.com/content.aspx?aID=2886966. Accessed Aug. 6, 2010.
DS00834 Sept. 25, 2010

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