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Definition

By Mayo Clinic staff

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Illustration showing celiac disease
Celiac disease

Digestive Health

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Celiac (SEE-lee-ak) disease is a digestive condition triggered by consumption of the protein gluten, which is primarily found in bread, pasta, cookies, pizza crust and many other foods containing wheat, barley or rye. People with celiac disease who eat foods containing gluten experience an immune reaction in their small intestines, causing damage to the inner surface of the small intestine and an inability to absorb certain nutrients.

Celiac disease can cause abdominal pain and diarrhea. Eventually, the decreased absorption of nutrients (malabsorption) that occurs with celiac disease can cause vitamin deficiencies that deprive your brain, peripheral nervous system, bones, liver and other organs of vital nourishment.

No treatment can cure celiac disease. However, you can effectively manage celiac disease by changing your diet.

References
  1. Farrel RJ, et al. Celiac disease and refractory celiac disease. In: Feldman M, et al. Sleisinger and Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, Pa.: Saunders; 2010. http://www.mdconsult.com/book/player/linkTo?type=bookHome&isbn=978-1-4160-6189-2&eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&uniq=200844987-3. Accessed Nov. 2, 2010.
  2. Ferri FF. Celiac disease. In: Ferri FF. Ferri's Clinical Advisor 2011. Philadelphia, Pa.: Mosby; 2010. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-323-05610-6..C2009-0-38600-6--TOP&isbn=978-0-323-05610-6&uniq=210978719. Accessed Nov. 2, 2010.
  3. Rubio-Tapia A, et al. Celiac disease. Current Opinion in Gastroenterology. 2010;26:116.
  4. Celiac disease nutrition therapy. ADA Nutrition Care Manual. http://nutritioncaremanual.org/index.cfm. Accessed Nov. 2, 2010.
  5. Celiac disease. National Institute for Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/celiac/index.htm. Accessed Nov. 4, 2010.
DS00319 Sept. 13, 2011

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