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Risk factors

By Mayo Clinic staff

Digestive Health

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Celiac disease can affect anyone. However, it tends to be more common in people who have:

  • A family member with celiac disease or dermatitis herpetiformis
  • Type 1 diabetes
  • Down syndrome or Turner syndrome
  • Autoimmune thyroid disease
  • Sjogren's syndrome
  • Microscopic colitis (lymphocytic or collagenous colitis)
References
  1. Ludvigsson JF, et al. The Oslo definitions for coeliac disease and related terms. Gut. 2013;62:43.
  2. AskMayoExpert. What are the most common manifestations of celiac disease today? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
  3. Celiac disease. National Digestive Diseases Information Clearinghouse. http://digestive.niddk.nih.gov/ddiseases/pubs/indigestion/index.aspx. Accessed March 20, 2013.
  4. Scanlon SA, et al. Update on celiac disease — etiology, differential diagnosis, drug targets, and management advances. Clinical and Experimental Gastroenterology. 2011;4:297.
  5. Rashtak S, et al. Review article: Coeliac disease, new approaches to therapy. Alimentary Pharmacology & Therapeutics. 2012;35:768.
  6. Rubio-Tapia A, et al. The prevalence of celiac disease in the United States. American Journal of Gastroenterology. 2012;107:1538.
  7. Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229935664-2192. Accessed March 21, 2013.
  8. Rubio-Tapia, A, et al. Prevalence of small intestine bacterial overgrowth diagnosed by quantitative culture of intestinal aspirate in celiac disease. Journal of Clinical Gastroenterology. 2009;43:157.
  9. Rubio-Tapia A, et al. Classification and management of refractory coeliac disease. Gut. 2010;59:547. Accessed March 29, 2013.
  10. Walker MM, et al. An update in the diagnosis of coeliac disease. Histopathology. 2011;59:166.
  11. Rubio-Tapia A, et al. Increased prevalence and mortality in undiagnosed celiac disease. Gastroenterology. 2009;137:88.
  12. Presutti, RJ. Celiac disease. American Family Physician. 2007;76:1795.
DS00319 May 22, 2013

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