Causes
By Mayo Clinic staffCerebral palsy is caused by an abnormality or disruption in brain development, usually before a child is born. In many cases, the exact trigger of this abnormality isn't known. Factors that may lead to problems with brain development include:
- Random mutations in genes that control brain development.
- Maternal infections that affect the developing fetus.
- Fetal stroke, a disruption of blood supply to the developing brain.
- Lack of oxygen to the brain (asphyxia) related to difficult labor or delivery. This is rarely a cause.
- Infant infections that cause inflammation in or around the brain.
- Traumatic head injury to an infant from a motor vehicle accident or fall.
References
- Cerebral palsy: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/cerebral_palsy/detail_cerebral_palsy.htm. Accessed May 8, 2013.
- Shelov SP, et al. Caring for Your Baby and Young Child: Birth to Age 5. 5th ed. New York, N.Y.: Bantam Books; 2009:1.
- Miller G. Epidemiology and etiology of cerebral palsy. http://www.uptodate.com/home. Accessed May 22, 2013.
- Miller G. Diagnosis and classification of cerebral palsy. http://www.uptodate.com/home. Accessed May 22, 2013.
- Miller G. Clinical features of cerebral palsy. http://www.uptodate.com/home. Accessed May 22, 2013.
- Rubella: Make sure your child gets vaccinated. Centers for Disease Control and Prevention. http://www.cdc.gov/Features/Rubella/. Accessed May 23, 2013.
- Chickenpox (varicella). Centers for Disease Control and Prevention. http://www.cdc.gov/chickenpox/about/overview.html. May 23, 2013.
- Cytomegalovirus (CMV) and congenital CMV infection: Pregnancy. Centers for Disease Control and Prevention. http://www.cdc.gov/cmv/risk/preg-women.html. Accessed May 23, 2013.
- Parasites: Toxoplasmosis (toxoplasma infection). Centers for Disease Control and Prevention. http://www.cdc.gov/parasites/toxoplasmosis/. Accessed May 23, 2013.
- Syphilis: CDC fact sheet. Centers for Disease Control and Prevention. http://www.cdc.gov/std/syphilis/STDFact-Syphilis.htm. Accessed May 23, 2013.
- Meningitis. Centers for Disease Control and Prevention. http://www.cdc.gov/meningitis/index.html. Accessed May 23, 2013.
- Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed May 24, 2013.
- Miller G. Management and prognosis of cerebral palsy. http://www.uptodate.com/home. Accessed May 22, 2013.
- Riggin EA. Decision Support System. Mayo Clinic, Rochester, Minn. May 23, 2013.
- Kotagal S (expert opinion). Mayo Clinic, Rochester, Minn. June 24, 2013.


Find Mayo Clinic on