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Complications

By Mayo Clinic staff

Treatments for invasive cervical cancer often make it impossible to become pregnant in the future. For many women — especially younger women and those who have yet to begin a family — infertility is a distressing side effect of treatment. If you're concerned about your ability to get pregnant in the future, discuss this with your doctor.

For a specific subgroup of women with early cervical cancer, fertility-sparing surgery may be a treatment option. A surgical procedure to remove only your cervix and surrounding lymphatic tissue (radical trachelectomy) may preserve your uterus.

Studies of radical trachelectomy suggest that cervical cancer can be cured using this technique, though it isn't appropriate for every woman and there may be added risks to this surgery. Future pregnancies are possible, but must be managed carefully because removing the cervical tissue can lead to a higher incidence of miscarriage and premature birth.

Tell your doctor about your concerns about infertility before your treatment begins. In most cases, preserving fertility is more successful than trying to restore fertility after treatment.

References
  1. Warren JB, et al. Cervical cancer screening and updated Pap guidelines. Primary Care: Clinics in Office Practice. 2009;36:131.
  2. Molpus KL, et al. Gynecologic cancers. In: Goldman L, et al., eds. Goldman: Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/135557788-7/837587224/1492/770.html#4-u1.0-B978-1-4160-2805-5..50214-7_9477. Accessed April 30, 2009.
  3. Zell JA, et al. Cancer prevention, screening and early detection. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2008. http://www.mdconsult.com/das/book/body/135557788-9/837588846/1709/31.html#4-u1.0-B978-0-443-06694-8..50030-0_657. Accessed April 30, 2009.
  4. How is cervical cancer diagnosed? American Cancer Society. Accessed April 30, 2009.
  5. What is cervical cancer? American Cancer Society. Accessed April 30, 2009.
  6. Holschneider CH, et al. Invasive cervical cancer: Management of early stage disease (FIGO IA, IB1, nonbulky IIA) and special circumstances. http://www.uptodate.com/home/index.html. Accessed April 30, 2009.
  7. Shepherd JH. Conservative surgery for carcinoma of the cervix. Clinical Oncology. 2008;20:395.
  8. Cervical cancer. Centers for Disease Control and Prevention. http://www.cdc.gov/cancer/cervical/pdf/cervical_facts.pdf. Accessed April 30, 2009.
  9. Holschneider CH. Invasive cervical cancer: Epidemiology, clinical features, and diagnosis. http://www.uptodate.com/home/index.html. Accessed April 30, 2009.
  10. Cervical cancer. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/cervical/Patient/page2. Accessed April 30, 2009.
  11. Detailed guide: Cervical cancer treatment options by stage. American Cancer Society. Accessed April 30, 2009.
  12. Holschneider CH, et al. Invasive cervical cancer: Management of stages IB2, bulky IIA, and locally advanced disease. http://www.uptodate.com/home/index.html. Accessed April 30, 2009.
  13. The emotional impact of a cancer diagnosis. American Cancer Society. Accessed April 30, 2009.
  14. Pap test. National Women's Health Information Center. http://www.womenshealth.gov/faq/pap-test.cfm. Accessed April 30, 2009.
  15. HPV vaccine information for young women. Centers for Disease Control and Prevention. http://www.cdc.gov/std/hpv/STDFact-HPV-vaccine-young-women.htm. Accessed April 30, 2009.
  16. Your first gynecologic visit. American College of Obstetrics and Gynecology. http://www.acog.org/publications/patient_education/bp150.cfm?printerFriendly=yes. Accessed April 30, 2009.
  17. Moynihan TJ (expert opinion). Mayo Clinic, Rochester, Minn. May 12, 2009.
  18. Cervical cytology screening. Washington, D.C.: American College of Obstetricians and Gynecologists. http://journals.lww.com/greenjournal/documents/PB109_Cervical_Cytology_Screening.pdf. Accessed Nov. 20, 2009.

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Nov. 21, 2009

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