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Risk factors

By Mayo Clinic staff

Living With Cancer

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These factors may increase your risk of cervical cancer:

  • Many sexual partners. The greater your number of sexual partners — and the greater your partner's number of sexual partners — the greater your chance of acquiring HPV.
  • Early sexual activity. Having sex at an early age increases your risk of HPV.
  • Other sexually transmitted infections (STIs). If you have other STIs — such as chlamydia, gonorrhea, syphilis or HIV/AIDS — you have an increased risk of having HPV.
  • A weak immune system. Most women who are infected with HPV never develop cervical cancer. However, if you have an HPV infection and your immune system is weakened by another health condition, you may be more likely to develop cervical cancer.
  • Cigarette smoking. Smoking and an HPV infection may work together to cause cervical cancer.
References
  1. Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2008. http://www.mdconsult.com/das/book/body/208746819-4/0/1709/0.html. Accessed May 8, 2013.
  2. Cervical cancer. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed May 8, 2013.
  3. What you need to know about cervical cancer. National Cancer Institute. http://www.cancer.gov/cancertopics/wyntk/cervix. Accessed May 8, 2013.
  4. Lentz GM, et al. Comprehensive Gynecology. 6th ed. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/linkTo?type=bookPage&isbn=978-0-323-06986-1&eid=4-u1.0-B978-0-323-06986-1..C2009-0-48752-X--TOP. Accessed May 8, 2013.
  5. Cervical cancer screening. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed May 8, 2013.
  6. HPV (human papillomavirus) vaccine: Gardasil. What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/vac-gen/side-effects.htm#hpvgardasil. Accessed May 8, 2013.
  7. HPV (human papillomavirus) vaccine: Cervarix. What you need to know. Centers for Disease Control and Prevention. http://www.cdc.gov/vaccines/vac-gen/side-effects.htm#hpvgardasil. Accessed May 8, 2013.
  8. Committee on Infectious Diseases. HPV vaccine recommendations. Pediatrics. 2012;129:602.
  9. Taking time: Support for People with Cancer. National Cancer Institute. http://cancer.gov/cancertopics/takingtime. Accessed May 9, 2013.
DS00167 June 28, 2013

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