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Symptoms
By Mayo Clinic staffSigns and symptoms of Charcot-Marie-Tooth disease may include:
- Weakness in your legs, ankles and feet
- Loss of muscle bulk in legs and feet
- High foot arches
- Curled toes (hammertoes)
- Decreased ability to run
- Difficulty lifting your foot at the ankle (footdrop)
- Awkward or higher than normal step (gait)
- Frequent tripping or falling
- Decreased sensation or a loss of feeling in your legs and feet
As Charcot-Marie-Tooth disease progresses, symptoms may not be limited to the feet and legs but may also involve the hands and arms. The severity of symptoms can vary greatly from person to person. This is true even among family members.
References
- Charcot-Marie-Tooth disease fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/charcot_marie_tooth/detail_charcot_marie_tooth.htm. Accessed Jan. 10, 2013.
- Facts about Charcot-Marie-Tooth disease and related diseases. Muscular Dystrophy Association. http://www.mda.org/publications/facts-about-charcot-marie-tooth-related-diseases. Accessed Jan. 12, 2013.
- Aminoff MJ, et al. Clinical Neurology. 7th ed. New York, N.Y.: The McGraw-Hill Companies; 2009. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=66. Accessed Jan. 9, 2013.
- Patzko A, et al. Update on Charcot-Marie-Tooth disease. Current Neurology Neuroscience Report. 2011;11:78.
- Patzko A, et al. Charcot-Marie-Tooth disease and related genetic neuropathies. Continuum Lifelong Learning in Neurology. 2012;18:39.
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