Chemical peel

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Risks

By Mayo Clinic staff

A chemical peel can cause various side effects, including:

  • Redness. A chemical peel will cause treated skin to become red. After a medium or deep chemical peel, redness might last for several months.
  • Scarring. Rarely, a chemical peel can cause scarring — typically on the lower part of the face. Antibiotics and steroid medications can be used to soften the appearance of these scars.
  • Changes in skin color. A chemical peel can cause treated skin to become darker than normal (hyperpigmentation) or lighter than normal (hypopigmentation). Hyperpigmentation is more common after superficial peels, while hypopigmentation is more common after a deep peel. Changes in skin color are more common in people who have darker skin and can be permanent.
  • Acne. Tiny white bumps (milia) on the skin are possible after a chemical peel. Acne also commonly develops as treated skin heals — due to previous acne or the use of oily creams on newly formed skin.
  • Infection. A chemical peel can cause a flare-up of the herpes virus — the virus that causes cold sores. Rarely, a chemical peel can lead to a bacterial or fungal infection.
  • Heart, kidney or liver damage. A deep chemical peel uses carbolic acid (phenol), which can damage the heart muscle and cause the heart to beat irregularly. Phenol can also harm the kidneys and liver. To limit exposure to phenol, a deep chemical peel is done in portions at 10- to 20-minute intervals.

A chemical peel isn't for everyone. Your doctor might caution against a chemical peel or certain types of chemical peels if you:

  • Have taken the acne medication isotretinoin (Amnesteem, others) in the past six months
  • Have a dark complexion
  • Have red hair and a pale, freckled complexion
  • Have a personal history of ridged areas caused by an overgrowth of scar tissue (keloids)
  • Have abnormal skin pigmentation
  • Have facial warts
  • Are pregnant or breast-feeding
References
  1. Bernstein EF. Chemical peels. Seminars in Cutaneous Medicine and Surgery. 2002;21:27.
  2. Friedman S, et al. Chemical peels, dermabrasion and laser therapy. 2009;55:223.
  3. Landau M. Chemical peels. Clinics in Dermatology. 2008;26:200.
  4. Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: The McGraw-Hill Companies; 2008. http://www.accessmedicine.com/content.aspx?aID=3007358. Accessed March 27, 2012.
  5. Chemical peel. American Society of Plastic Surgeons. http://www.plasticsurgery.org/cosmetic-procedures/chemical-peel.html. Accessed March 27, 2012.
  6. Chemical peel information. American Society for Dermatologic Surgery. http://www.asds.net/_ConsumerPage.aspx?id=508&terms=chemical%20peel#. Accessed March 27, 2012.
  7. Facial peels and laser surgery. The American Academy of Facial Plastic and Reconstructive Surgery. http://www.aafprs.org/patient/procedures/resurfacing.html. Accessed March 27, 2012.
  8. Roenigk RK, et al. Roenigk's Dermatologic Surgery: Current Techniques in Procedural Dermatology. New York, N.Y.: Informa Healthcare;2007:763.
  9. Gibson LE (expert opinion). Mayo Clinic, Rochester, Minn. April 18, 2012.
MY02019 May 30, 2012

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