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Causes

By Mayo Clinic staff

The underlying causes of childhood asthma aren't fully understood. Developing an overly sensitive immune system generally plays a role. Some factors thought to be involved include:

  • Inherited traits
  • Some types of airway infections at a very young age
  • Exposure to environmental factors, such as cigarette smoke or other air pollution

Increased immune system sensitivity causes the lungs and airways to swell and produce mucus when exposed to certain triggers. Reaction to a trigger may be delayed, making it more difficult to identify the trigger. These triggers vary from child to child and can include:

  • Viral infections such as the common cold
  • Exposure to air pollutants, such as tobacco smoke
  • Allergies to dust mites, pet dander, pollen or mold
  • Physical activity
  • Weather changes or cold air

Sometimes, asthma symptoms occur with no apparent triggers.

References
  1. Kliegman RM, et al. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/208746819-6/0/1608/0.html. Accessed Nov. 27, 2012.
  2. Childhood asthma: Tips to remember. American Academy of Allergy, Asthma & Immunology. http://www.aaaai.org/conditions-and-treatments/library/at-a-glance/childhood-asthma.aspx. Accessed Nov. 27, 2012.
  3. Expert panel report 3 (EPR-3): Guidelines for the diagnosis and management of asthma. Bethesda, Md.: National Institutes of Health. http://www.nhlbi.nih.gov/guidelines/asthma/06_sec3_comp3.pdf. Accessed Nov. 27, 2012.
  4. Krystofova J, et al. Bronchial asthma and obesity in childhood. Acta Medica. 2011;54:102.
  5. Hay WW, et al. Current Diagnosis & Treatment: Pediatrics. 20th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=14. Accessed Nov. 27, 2012.
  6. Bacherier LB, et al. Diagnosis and management of early asthma in pre-school aged children. Journal of Allergy and Clinical Immunology. 2012;130:287.
  7. Childhood asthma. Asthma and Allergy Foundation of America. http://www.aafa.org/print.cfm?id=8&sub=16&cont=44. Accessed Nov. 27, 2012.
  8. Young C. Avoiding asthma triggers: A primer for patients. Journal of the American Osteopathic Association. 2011;111:S30.
  9. Bukutu C, et al. Asthma: A review of complementary and alternative therapies. Pediatrics in Review. 2008;29:e44.
  10. Torres-Llenza V, et al. Use of complementary and alternative medicine in children with asthma. Canadian Respiratory Journal. 2010;17:183.
  11. Li JTC (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 29, 2012.
DS00849 March 5, 2013

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