Childhood schizophrenia

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Causes

By Mayo Clinic staff

It's not known what causes childhood schizophrenia, but it's thought that it develops in the same way as adult schizophrenia does. It's not clear why schizophrenia starts so early in life for some, though, and not others.

Childhood schizophrenia and other forms of schizophrenia are brain disorders. Genetics and environment likely both play a role in causing schizophrenia.

Problems with certain naturally occurring brain chemicals called neurotransmitters may contribute to childhood schizophrenia. Imaging studies show differences in the brain structure of people with schizophrenia, but the significance of these changes isn't clear.

References
  1. Schizophrenia. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed Oct. 12, 2010.
  2. Schizophrenia. Skodol AE, et al. Specific personality disorders. In: Hales RE, et al., eds. The American Psychiatric Publishing Textbook of Psychiatry. 5th ed. Arlington, Va.: American Psychiatric Association; 2008. http://www.psychiatryonline.com. Accessed Oct. 12, 2010.
  3. Jibson MD. Schizophrenia: Clinical presentation, epidemiology, and pathophysiology. http://www.uptodate.com/home/index.html. Accessed Oct. 12, 2010.
  4. Gejman PV, et al. The role of genetics in the etiology of schizophrenia. Psychiatric Clinics of North America. 2010;33:3.
  5. Schizophrenia. National Institute of Mental Health. http://www.nimh.nih.gov/health/publications/schizophrenia/complete-publication.shtml. Accessed Oct. 12, 2010.
  6. Jibson MD. Schizophrenia: Diagnostic evaluation and treatment. http://www.uptodate.com/home/index.html. Accessed Oct. 12, 2010.
  7. Families and schizophrenia: The view from advocacy. Psychiatric Clinics of North America. 2007;30:549.
  8. Rathod SR, et al. Cognitive behavioral therapy for schizophrenia. Psychiatric Clinics of North America. 2010;33:3.
  9. Staying well when you have a mental health condition. Mental Health America. http://www.nmha.org/go/mental-health-month/staying-well-when-you-have-a-mental-illness. Accessed Oct. 12, 2010.
  10. Mattai AK, et al. Treatment of early-onset schizophrenia. Current Opinion in Psychiatry. 2010;23:304.
  11. Frazier JA, et al. Treatment of early-onset schizophrenia spectrum disorders (TEOSS): Demographic and clinical characteristics. Journal of the American Academy of Child and Adolescent Psychiatry. 2007;46:979.
  12. Early onset schizophrenia. National Alliance on Mental Illness. http://www.nami.org/Content/ContentGroups/Helpline1/Early_Onset_Schizophrenia.htm. Accessed Oct. 12, 2010.
  13. Factsheet: Schizophrenia in children. Mental Health America. http://www.nmha.org/index.cfm?objectId=C7DF8F81-1372-4D20-C84C5539FAB14576. Accessed Oct. 12, 2010.
  14. Wall CA (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 17, 2010.
DS00868 Dec. 17, 2010

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