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Causes

By Mayo Clinic staff

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Image showing gallbladder and bile duct 
Gallbladder and bile duct

Cholecystitis occurs when your gallbladder becomes inflamed. Gallbladder inflammation can be caused by:

  • Gallstones. The vast majority of cholecystitis cases are the result of gallstones that block the cystic duct — the tube through which bile flows when it leaves the gallbladder — causing bile to build up and resulting in gallbladder inflammation.
  • Tumor. A tumor may prevent bile from draining out of your gallbladder properly, causing bile buildup that can lead to cholecystitis.
  • Bile duct blockage. Kinking or scarring of the bile ducts can cause blockages that lead to cholecystitis.
References
  1. Cholecystitis. In: Ferri FF. Ferri's Clinical Advisor 2012: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-05610-6..C2009-0-38600-6--TOP&isbn=978-0-323-05610-6&about=true&uniqId=230100505-53. Accessed July 22, 2011.
  2. Wang DQH, et al. Gallstone disease. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229935664-2192. Accessed July 22, 2011.
  3. Guss DA, et al. Disorders of the liver and biliary tract. In: Marx JA, et al. Rosen's Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa.: Mosby Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-323-05472-0..X0001-1--TOP&isbn=978-0-323-05472-0&uniqId=230019911-17. Accessed July 22, 2011.
  4. Gallstones. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/gallstones/index.aspx. Accessed July 22, 2011.
DS01153 Sept. 1, 2011

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