CausesBy Mayo Clinic staff
The cause of cholestasis of pregnancy is unknown. However, the condition may be related to pregnancy hormones.
Bile — a digestive fluid that helps the body break down fats — is produced in the liver and stored in the gallbladder. Pregnancy hormones can affect how well the gallbladder functions. Sometimes, pregnancy hormones slow or even stop the flow of bile. Eventually, this excess bile may enter the bloodstream. This is cholestasis of pregnancy.
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