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Symptoms
By Mayo Clinic staffSigns and symptoms of cholestasis of pregnancy may include:
- Intense itching
- Dark-colored urine
- Light-colored bowel movements
- Yellow eyes or skin
Often, however, intense itching — particularly on the palms of the hands and the soles of the feet — is the only symptom of cholestasis of pregnancy. The itching may be worse, even intolerable, at night. The itching is most common during the third trimester of pregnancy, but sometimes begins earlier.
When to see a doctor
Contact your health care provider if you develop any signs or symptoms of cholestasis of pregnancy.
- Bacq Y. Intrahepatic cholestasis of pregnancy. http://www.uptodate.com/home/index.html. Accessed Aug. 21, 2009.
- Geenes V, et al. Intrahepatic cholestasis of pregnancy. World Journal of Gastroenterology. 2009;15:2049.
- Liver disorders in pregnancy. March of Dimes. http://www.marchofdimes.com/professionals/14332_14543.asp. Accessed Aug. 24, 2009.
- Riely CA, et al. Intrahepatic cholestasis of pregnancy. Clinics in Liver Disease. 2004;8:167.
- Skin conditions during pregnancy. The American College of Obstetricians and Gynecologists. http://www.acog.org/publications/patient_education/bp169.cfm. Accessed Aug. 24, 2009.
- Cappell MS. Hepatic and gastrointestinal diseases. In: Gabbe SG, et al. Obstetrics: Normal and Problem Pregnancies. 5th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2007. http://www.mdconsult.com/das/book/body/156403804-2/0/1528/432.html?tocnode=57028110&fromURL=432.html. Accessed Aug. 24, 2009.
- Burrows R, et al. Interventions for treating cholestasis in pregnancy. Cochrane Database of Systematic Reviews. 2009:CD000493.
- SAMe. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Sept. 9, 2009.
