Chronic cough

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Causes

By Mayo Clinic staff

An occasional cough is normal — it helps clear foreign substances and secretions from your lungs and prevents infection. But a cough that persists for long periods of time is usually the result of an underlying problem. Examples include:

  • Postnasal drip. When your nose or sinuses produce extra mucus, it can drip down the back of your throat and trigger your cough reflex.
  • Asthma. An asthma-related cough may come and go with the seasons, appear after an upper respiratory tract infection, or become worse when you're exposed to cold air or certain chemicals or fragrances. This type of asthma is frequently referred to as hyperactive airways disease.
  • Gastroesophageal reflux disease (GERD). In this common condition, stomach acid flows back into the tube that connects your stomach and throat (esophagus). The constant irritation can lead to chronic coughing.
  • Infections. A cough can linger long after most symptoms of a cold, influenza, pneumonia or other infection of the upper respiratory tract have gone away. An unusual, but not rare, cause of a chronic cough in adults is pertussis, also known as whooping cough in children.
  • Blood pressure drugs. Angiotensin-converting enzyme (ACE) inhibitors, which are commonly prescribed for high blood pressure and heart failure, are known to cause chronic cough in some people.
  • Chronic bronchitis. This long-standing inflammation of your major airways (bronchial tubes) can cause congestion, breathlessness, wheezing and a cough that brings up discolored sputum. Most people with chronic bronchitis are current or former smokers.
References
  1. Cough. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/cough/cough_all.html. Accessed March 11, 2011.
  2. Chung KF, et al. Cough. In: Mason RJ, et al. Murray and Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/das/book/body/192068760-2/0/1288/0.html. Accessed March 11, 2011.
  3. Kraft M. Approach to the patient with cough. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed March 11, 2011.
  4. Silvestri RC, et al. Evaluation of subacute and chronic cough in adults. http://www.uptodate.com/home/index.html. Accessed March 11, 2011.
  5. Weinberger SE, et al. Treatment of subacute and chronic cough in adults. http://www.uptodate.com/home/index.html. Accessed March 14, 2011.
DS00957 May 14, 2011

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