Treatments and drugsBy Mayo Clinic staff
Treatment for chronic fatigue syndrome focuses on symptom relief.
- Antidepressants. Many people who have chronic fatigue syndrome are also depressed. Treating your depression can make it easier for you to cope with the problems associated with chronic fatigue syndrome. And low doses of some antidepressants also can help improve sleep and relieve pain.
- Sleeping pills. If home measures, such as avoiding caffeine, don't help you get better rest at night, your doctor might suggest trying prescription sleep aids.
The most effective treatment for chronic fatigue syndrome appears to be a two-pronged approach that combines psychological counseling with a gentle exercise program.
- Graded exercise. A physical therapist can help determine what types of exercise are best for you. Inactive people often begin with range-of-motion and stretching exercises for just a few minutes a day. If you're exhausted the next day, you're doing too much. Your strength and endurance will improve as you gradually increase the intensity of your exercise over time.
- Psychological counseling. Talking with a counselor can help you figure out options to work around some of the limitations that chronic fatigue syndrome imposes on you. Feeling more in control of your life can improve your outlook dramatically.
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