Complications
By Mayo Clinic staffComplications of hives and angioedema may include:
- Itching. Hives and angioedema can cause itching and discomfort.
- Difficulty breathing. In more-serious cases — when swelling occurs inside your mouth or throat — complications can include difficulty breathing, leading to a loss of consciousness. If you have a swollen throat, seek medical care immediately.
- Anaphylactic shock (anaphylaxis). This is a serious allergic reaction involving your heart or lungs that can also be associated with hives and angioedema. Your bronchial tubes narrow, it's difficult to breathe, and your blood pressure drops, causing dizziness and perhaps loss of consciousness or even death. Anaphylactic shock occurs rapidly and requires immediate medical care.
References
- Hives. American Academy of Dermatology. http://www.aad.org/skin-conditions/dermatology-a-to-z/hives. Accessed April 3, 2011.
- All about hives (urticaria). American College of Allergy, Asthma and Immunology. http://www.acaai.org/allergist/allergies/Types/skin-allergies/hives/Pages/default.aspx. Accessed April 3, 2011.
- Khan DA. Chronic urticaria: Standard management and patient education. http://www.uptodate.com/home/index.html. Accessed April 9, 2011.
- Kaplan AP. Urticaria and angioedema. In: Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, NY.: The McGraw-Hill Companies. 2008. http://www.accessmedicine.com/content.aspx?aID=2958607&searchStr=urticaria#2958607. Accessed April 11, 2011.
- Kropfl L, et al. Treatment strategies in urticaria. Expert Opinion on Pharmacotherapy. 2010;11:1445.
- Bingham CO. New onset urticaria: Epidemiology, clinical manifestations, and etiologies. http://www.uptodate.com/home/index/html. Accessed April 9, 2011.
- Limsuwan T, et al. Acute symptoms of drug hypersensitivity (Urticaria, angioedema, anaphylaxis, anaphylactic shock). The Medical Clinics of North America. 2010;94:691.
- Hives: Tips for managing. American Academy of Dermatology. http://www.aad.org/skin-conditions/dermatology-a-to-z/hives/tips/hives-tips-for-managing. Accessed April 11, 2011.
- Peroni A, et al. Urticarial lesions: If not urticaria, what else? The differential diagnoses of urticaria. Journal of the American Academy of Dermatology. 2010;62:557.
- Bingham CO. New onset urticaria: Diagnosis and treatment. http://www.uptodate.com/home/index/html. Accessed April 9, 2011.
- FDA requests labeling change for leukotriene modifiers. U.S. Food and Drug Administration. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2009/ucm166293.htm. Accessed April 12, 2011.
- Immunosuppressant drugs: Required labeling changes. U.S. Food and Drug Administration. http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm171828.htm. Accessed April 12, 2011.
- Urticaria treatment. American College of Allergy, Asthma and Immunology. http://www.acaai.org/allergist/allergies/Types/skin-allergies/hives/Pages/urticaria-hives-treatment.aspx. Accessed April 8, 2011.


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