Risk factorsBy Mayo Clinic staff
Factors that may increase the risk of chronic lymphocytic leukemia include:
- Your age. Most people diagnosed with chronic lymphocytic leukemia are older than 60.
- Your sex. Men are more likely than are women to develop chronic lymphocytic leukemia.
- Your race. Whites are more likely to develop chronic lymphocytic leukemia than are people of other races.
- Family history of blood and bone marrow cancers. A family history of chronic lymphocytic leukemia or other blood and bone marrow cancers may increase your risk.
- Exposure to chemicals. Certain herbicides and insecticides, including Agent Orange used during the Vietnam War, have been linked to an increased risk of chronic lymphocytic leukemia.
- Lichtman MA, et al. Williams Hematology. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2010. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=69. Accessed March 7, 2013.
- Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2008. http://www.mdconsult.com/das/book/body/208746819-4/0/1709/0.html. Accessed March 7, 2013.
- Chronic lymphocytic leukemia. The Leukemia & Lymphoma Society. http://www.lls.org/#/resourcecenter/freeeducationmaterials/leukemia/cll. Accessed March 7, 2013.
- Chronic lymphocytic leukemia treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/CLL/patient. Accessed March 7, 2013.
- When cancer doesn't go away. American Cancer Society. http://www.cancer.org/treatment/survivorshipduringandaftertreatment/when-cancer-doesnt-go-away. Accessed March 7, 2013.
- Cancer-related fatigue. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed March 7, 2013.
- Shanafelt TD, et al. Phase 2 trial of daily, oral polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia. Cancer. 2013;119:363.
- Green tea. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed March 7, 2013.
- Shanafelt TD, et al. Hematologist/oncologist disease-specific expertise and survival: Lessons from chronic lymphocytic leukemia (CLL)/small lymphocytic leukemia (SLL). Cancer. 2012;118:1827.
- Shanafelt TD (expert opinion). Mayo Clinic, Rochester, Minn. April 2, 2013.