Chronic lymphocytic leukemia

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Symptoms

By Mayo Clinic staff

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Many people with chronic lymphocytic leukemia have no symptoms. Those who do develop signs and symptoms may experience:

  • Enlarged, but painless, lymph nodes
  • Fatigue
  • Fever
  • Pain in the upper left portion of the abdomen, which may be caused by an enlarged spleen
  • Night sweats
  • Weight loss
  • Frequent infections

When to see a doctor
Make an appointment with your doctor if you're concerned about any of your signs and symptoms.

Causes Definition
References
  1. Kipps TJ. Chronic lymphocytic leukemia and related diseases. In: Lichtman MA, et al. Williams Hematology. 8th ed. New York, N.Y.: McGraw-Hill Companies; 2010. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=69. Accessed Sept. 16, 2010.
  2. Grever MR, et al. Chronic lymphoid leukemias. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2007:2293.
  3. Elphee EE. Caring for patients with chronic lymphocytic leukemia. Clinical Journal of Oncology Nursing. 2008;12:417.
  4. Chronic lymphocytic leukemia treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/CLL/patient/allpages. Accessed Sept. 15, 2010.
  5. Arzerra (prescribing information). Research Park Triangle, N.C.: GlaxoSmithKline; 2009. http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/125326lbl.pdf. Accessed Sept. 15, 2010.
  6. Cancer-related fatigue. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/fatigue.pdf. Accessed Sept. 15, 2010.
  7. Shanafelt TD, et al. Phase I trial of daily oral polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia. Journal of Clinical Oncology. 2009;27:3808.
  8. Green tea. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Sept. 24, 2010.
DS00565 Nov. 24, 2010

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