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Housecall, our weekly general-interest e-newsletter, keeps you up to date on a wide variety of health topics with timely, reliable, practical information, recipes, blogs, questions and answers with Mayo Clinic experts and more. Our biweekly topic-specific e-newsletters also include blogs, questions and answers with Mayo Clinic experts, and other useful information that will help you manage your health.
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Symptoms
By Mayo Clinic staffMany people with chronic lymphocytic leukemia have no symptoms. Those who do develop signs and symptoms may experience:
- Enlarged, but painless, lymph nodes
- Fatigue
- Fever
- Night sweats
- Weight loss
- Frequent infections
When to see a doctor
Make an appointment with your doctor if you're concerned about any of your signs and symptoms.
References
- Montserrat E, et al. Chronic lymphocytic leukaemia: A short overview. Annals of Oncology. 2008;19(suppl):vii320.
- Caligaris-Cappio F, et al. Novel insights in chronic lymphocytic leukemia: Are we getting closer to understanding the pathogenesis of the disease? Journal of Clinical Oncology. 2008;26:4497.
- Elphee EE. Caring for patients with chronic lymphocytic leukemia. Clinical Journal of Oncology Nursing. 2008;12:417.
- Dighiero G, et al. Chronic lymphocytic leukaemia. The Lancet. 2008;371(9617):1017.
- Nabhan C, et al. Controversies in the front-line management of chronic lymphocytic leukemia. Leukemia Research. 2008;32:679.
- Chronic lymphocytic leukemia treatment (PDQ) patient version. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/CLL/patient/allpage/print. Accessed Oct. 13, 2008.
- Hallek M, et al. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute Working Group 1996 guidelines. Blood. 2008;111:5446.
- SEER stat fact sheets. Surveillance Epidemiology and End Results. http://seer.cancer.gov/statfacts/html/clyl.html. Accessed Oct. 15, 2008.
- Questions about treatment. The Leukemia & Lymphoma Society. http://www.leukemia-lymphoma.org/graphics/National/Allquestionsworksheets/QuestionsabouttreatmentPS172R.pdf. Accessed Oct. 15, 2008.
- Campath (prescribing information). Cambridge, Mass.: Genzyme Corp.; 2007. http://www.fda.gov/cder/foi/label/2007/103948s5070lbl.pdf. Accessed Oct. 15, 2008.
- Rituxan (prescribing information). San Francisco, Calif.: Genentech; 2008. http://www.fda.gov/cder/foi/label/2008/103705s5256lbl.pdf. Accessed Oct. 15, 2008.
- Cancer-related fatigue. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/fatigue.pdf. Accessed Oct. 15, 2008.
- Shanafelt TD (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 12, 2008.
