Chronic lymphocytic leukemia


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Symptoms

By Mayo Clinic staff

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Many people with chronic lymphocytic leukemia have no early symptoms. Those who do develop signs and symptoms may experience:

  • Enlarged, but painless, lymph nodes
  • Fatigue
  • Fever
  • Pain in the upper left portion of the abdomen, which may be caused by an enlarged spleen
  • Night sweats
  • Weight loss
  • Frequent infections

When to see a doctor
Make an appointment with your doctor if you're concerned about any of your signs and symptoms.

Causes Definition
References
  1. Lichtman MA, et al. Williams Hematology. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2010. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=69. Accessed March 7, 2013.
  2. Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2008. http://www.mdconsult.com/das/book/body/208746819-4/0/1709/0.html. Accessed March 7, 2013.
  3. Chronic lymphocytic leukemia. The Leukemia & Lymphoma Society. http://www.lls.org/#/resourcecenter/freeeducationmaterials/leukemia/cll. Accessed March 7, 2013.
  4. Chronic lymphocytic leukemia treatment (PDQ). National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/CLL/patient. Accessed March 7, 2013.
  5. When cancer doesn't go away. American Cancer Society. http://www.cancer.org/treatment/survivorshipduringandaftertreatment/when-cancer-doesnt-go-away. Accessed March 7, 2013.
  6. Cancer-related fatigue. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed March 7, 2013.
  7. Shanafelt TD, et al. Phase 2 trial of daily, oral polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia. Cancer. 2013;119:363.
  8. Green tea. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed March 7, 2013.
  9. Shanafelt TD, et al. Hematologist/oncologist disease-specific expertise and survival: Lessons from chronic lymphocytic leukemia (CLL)/small lymphocytic leukemia (SLL). Cancer. 2012;118:1827.
  10. Shanafelt TD (expert opinion). Mayo Clinic, Rochester, Minn. April 2, 2013.
DS00565 April 26, 2013

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