Chronic myelogenous leukemia

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Symptoms

By Mayo Clinic staff

Signs and symptoms of chronic myelogenous leukemia may include:

  • Easy bleeding
  • Feeling run-down or tired
  • Fever
  • Frequent infections
  • Losing weight without trying
  • Loss of appetite
  • Pain or fullness below the ribs on the left side
  • Pale skin
  • Sweating excessively during sleep (night sweats)

When to see a doctor
Chronic myelogenous leukemia doesn't always reveal itself with obvious signs and symptoms during the early phase. It's possible to live with chronic myelogenous leukemia for months or years without realizing it.

Because people with chronic myelogenous leukemia tend to respond better to treatment when it's started early, make an appointment with your doctor if you have signs or symptoms that bother you.

References
  1. Chronic myelogenous leukemia. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/cml.pdf. Accessed Sept. 11, 2008.
  2. Chronic myelogenous leukemia treatment (PDQ) patient version. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/CML/patient/allpages/patient. Accessed Sept. 11, 2008.
  3. Chronic myelogenous leukemia and related disorders: An overview. In: Lichtman MA, et al. Williams Hematology. 7th ed. New York, N.Y.: McGraw-Hill; 2006. http://www.accessmedicine.com/content.aspx?aID=2148618. Accessed Sept. 11, 2008.
  4. Leukemia - chronic myeloid - CML. Cancer.Net. http://www.cancer.net/patient/Cancer+Types/Leukemia+-+Chronic+Myeloid+-+CML. Accessed Sept. 17, 2008.
  5. Integrative medicine and complementary and alternative therapies as part of blood cancer care. The Leukemia & Lymphoma Society. http://www.leukemia-lymphoma.org/attachments/National/br_1150734030.pdf. Accessed Sept. 17, 2008.
  6. Questions about treatment. The Leukemia & Lymphoma Society. http://www.leukemia-lymphoma.org/graphics/National/Allquestionsworksheets/QuestionsabouttreatmentPS172R.pdf. Accessed Sept. 16, 2008.
  7. Kantarjian H, et al. Chronic myeloid leukemia. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2008:2279-2291.
  8. SEER stat fact sheets - chronic myeloid leukemia. Surveillance Epidemiology and End Results. http://seer.cancer.gov/statfacts/html/cmyl.html. Accessed Sept. 19, 2008.
  9. Tasignia (prescribing information). East Hanover, N.J.: Novartis; 2007.
  10. Gleevec (prescribing information). East Hanover, N.J.: Novartis; 2007.
  11. Sprycel (prescribing information). Princeton, N.J.: Bristol-Myers Squibb; 2007.

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Nov. 13, 2008

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