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Risk factors
By Mayo Clinic staffChurg-Strauss syndrome is rare, affecting as few as 1 to 3 people per million.
Possible risk factors for Churg-Strauss syndrome include:
- Age. On average, people with Churg-Strauss syndrome are diagnosed in their mid- to late 40s.
- History of asthma or nasal problems. Most people diagnosed with Churg-Strauss syndrome have a history of nasal allergies, chronic sinusitis or asthma, which is often severe or hard to control. It's important to note that while almost everyone with Churg-Strauss syndrome has asthma or allergies, most people with those conditions will never develop Churg-Strauss syndrome.
References
- Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed May 21, 2013.
- Vaglio A, et al. Churg-Strauss syndrome: Update on pathophysiology and treatment. Current Opinions in Rheumatology. 2012;24:24.
- Baldini C, et al. Clinical manifestations and treatment of Churg-Strauss syndrome. Rheumatic Disease Clinics of North America. 2010;36:527.
- Vaglio A, et al. Eosinophilic granulomatosis with polyangiitis (Churg-Strauss): State of the art. Allergy. 2013;68:261.
- King TE Jr. Clinical features and diagnosis of eosinophilic granulomatosis with polyangiitis (Churg-Strauss). http://www.uptodate.com/home. Accessed May 21, 2013.
- Paggiaro P, et al. Montelukast in asthma: A review of its efficacy and place in therapy. Therapeutic Advances in Chronic Disease. 2011;2:47.
- Bibby S, et al. Association between leukotriene receptor antagonist therapy and Churg-Strauss syndrome: An analysis of the FDA AERS database. Thorax. 2010;65:132.
- Imboden JB, et al. Current Rheumatology Diagnosis & Treatment. 2nd ed. New York, N.Y.: The McGraw-Hill Companies; 2007. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=38. Accessed May 21, 2013.
- Medication and side effects. The Churg-Strauss Syndrome Association. http://www.cssassociation.org/medications-and-side-effects.html. Accessed May 25, 2013.
- King TE Jr. Treatment and prognosis of Churg-Strauss syndrome of eosinophilic granulomatosis with polyangiitis (Churg-Strauss). http://www.uptodate.com/home. Accessed May 21, 2013.
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