Churg-Strauss syndrome

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Risk factors

By Mayo Clinic staff

It's not known precisely how many people have Churg-Strauss syndrome, but the disease is rare. Although may people may have risk factors for the disease, very few actually develop it.

Risk factors for Churg-Strauss syndrome include:

  • Age. On average, people with Churg-Strauss syndrome are diagnosed between ages 38 and 52. The disorder is rare in older adults and children.
  • History of asthma or nasal problems. Most people diagnosed with Churg-Strauss syndrome have a history of nasal allergies, chronic sinusitis or asthma, which is often severe or hard to control.
Complications Causes

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References
  1. Baldini C, et al. Clinical manifestations and treatment of Churg-Strauss syndrome. Rheumatic Disease Clinics of North America. 2010;36:527.
  2. Lee K, et al. Churg-Strauss syndrome. In: Ferri FF. Ferri's Clinical Advisor 2011: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2011. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-0-323-05610-6..00012-3--sc0165&isbn=978-0-323-05610-6&sid=1068342455&type=bookPage&sectionEid=4-u1.0-B978-0-323-05610-6..00012-3--sc0165&uniqId=222493850-3#4-u1.0-B978-0-323-05610-6..00012-3--sc0165. Accessed Oct. 12, 2010.
  3. Sneller MC, et al. Churg-Strauss syndrome. In: Adkinson NF, et al. Middleton's Allergy: Principles and Practice. 7th ed. St. Louis, Mo.: Mosby; 2008. http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-0-323-05659-5..00054-1--cesec15&isbn=978-0-323-05659-5&sid=1068342455&type=bookPage&sectionEid=4-u1.0-B978-0-323-05659-5..00054-1--cesec15&uniqId=222493850-3#4-u1.0-B978-0-323-05659-5..00054-1--cesec15. Accessed Oct. 12, 2010.
  4. King TE Jr. Clinical features and diagnosis of Churg-Strauss syndrome (allergic granulomatosis and angiitis). http://www.uptodate.com/home/index.html. Accessed Oct. 12, 2010.
  5. King TE Jr. Epidemiology, pathogenesis, and pathology of Churg-Strauss syndrome (allergic granulomatosis and angiitis). http://www.uptodate.com/home/index.html. Accessed Oct. 12, 2010.
  6. King TE Jr. Treatment and prognosis of Churg-Strauss syndrome (allergic granulomatosis and angiitis). http://www.uptodate.com/home/index.html. Accessed Oct. 12, 2010.
  7. Glucocorticoid-induced osteoporosis. American College of Rheumatology. http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/gi-osteoporosis.asp. Accessed Oct. 12, 2010.
  8. Cannon GW. Immunosuppressing drugs including corticosteroids. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/225194068-7/1078137300/1492/151.html#4-u1.0-B978-1-4160-2805-5..50038-0_1384. Accessed Nov. 2, 2010.
  9. Dietary supplement fact sheet: Vitamin D. National Institutes of Health. http://ods.od.nih.gov/factsheets/vitamind.asp. Accessed Oct. 12, 2010.
  10. Rosenow E (expert opinion). Mayo Clinic, Rochester, Minn. Oct. 19, 2010.
DS00855 Nov. 13, 2010

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