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Symptoms

By Mayo Clinic staff

Cirrhosis often has no signs or symptoms until liver damage is extensive. When signs and symptoms do occur, they may include:

  • Fatigue
  • Bleeding easily
  • Bruising easily
  • Itchy skin
  • Yellow discoloration in the skin and eyes (jaundice)
  • Fluid accumulation in your abdomen (ascites)
  • Loss of appetite
  • Nausea
  • Swelling in your legs
  • Weight loss

When to see a doctor
Make an appointment with your doctor if you have persistent signs or symptoms of cirrhosis.

References
  1. Sanchez W, et al. Liver cirrhosis. The American College of Gastroenterology. http://patients.gi.org/topics/liver-cirrhosis/. Accessed Dec. 3, 2012.
  2. 2. Ferri FF. Ferri's Clinical Advisor 2013:5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-08373-7..00002-9&isbn=978-0-323-08373-7&about=true&uniqId=343863096-23.Accessed Nov. 27, 2012.
  3. Cirrhosis. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.3.gov/ddiseases/pubs/cirrhosis/index.htm. Accessed Nov. 27, 2012.
  4. Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229935664-2192. Accessed Dec. 3, 2012.
  5. AskMayoExpert. What are the clinical manifestations of primary biliary cirrhosis (PBC)? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
  6. Starr PS, et al. Cirrhosis: Diagnosis, management and prevention. American Family Physician. 2011;84:1353.
  7. AskMayoExpert. What are the complications and comorbid conditions associated with primary biliary cirrhosis (PBC)? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
  8. Jafri SM, et al. Care of the cirrhotic patient. Infectious Disease Clinics of North America. 2012;26:979.
  9. AskMayoExpert. When should patients with cirrhosis be screened for esophageal varices? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2010.
  10. AskMayoExpert. What is the standard follow-up for patients receiving therapy for primary biliary cirrhosis (PBC)? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
  11. AskMayoExpert. What is the initial therapy recommended for patients with nonalcoholic fatty liver disease? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
  12. AskMayoExpert. Will asymptomatic patients who receive a diagnosis of primary biliary cirrhosis (PBC) have symptoms at a later time? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
  13. AskMayoExpert. What is the expected prognosis of primary biliary cirrhosis (PBC) following treatment? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
  14. Your liver. Your life. American Liver Foundation. http://www.yourliver.org/Liver-Wellness-Presentation.pdf. Accessed Dec. 3, 2012.
  15. Liver transplant. National Digestive Diseases Information Clearinghouse. http://digestive.niddk.nih.gov/ddiseases/pubs/livertransplant. Accessed Dec. 28, 2012.
  16. Verma S et al. Complementary and alternative medicine in hepatology: review of the evidence of efficacy. Clinical Gastroenterology and Hepatology. 2007; 5: 408.
  17. Rakel D. Integrative Medicine. 3rd ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/208746819-2/0/1494/0.html. Accessed Jan. 3, 2013.
DS00373 Jan. 30, 2013

© 1998-2013 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

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