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Risk factors

By Mayo Clinic staff

The risk factors for claudication are the same as those for developing atherosclerosis, including:

  • Smoking
  • High cholesterol
  • High blood pressure
  • Obesity (a body mass index over 30)
  • Diabetes
  • Age older than 70 years
  • Age older than 50 years if you also smoke or have diabetes
  • A family history of atherosclerosis, peripheral artery disease or claudication
References
  1. Mohler ER. Clinical features, diagnosis, and natural history of lower extremity peripheral arterial disease. http://www.uptodate.com/home/index.html. Accessed Nov. 18, 2011.
  2. Peripheral artery disease. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/cardiovascular_disorders/peripheral_arterial_disorders/peripheral_arterial_disease.html. Accessed Nov. 18, 2011.
  3. White C. Intermittent claudication. New England Journal of Medicine. 2007;356:1241.
  4. Rooke TW, et al. 2011 ACCF/AHA focused update of the guideline for the management of patients with peripheral artery disease (updating the 2005 guideline). Journal of the American College of Cardiology. 2011;58:2020.
  5. Rudisill HM, et al. Effective therapies for intermittent claudication. American Family Physician. 2011;84:699.
  6. Vodnala D, et al. Medical management of the patient with intermittent claudication. Cardiology Clinics. 2011;39:363.
  7. Ahimastos AA, et al. A meta-analysis of the outcome of endovascular and noninvasive therapies in the treatment of intermittent claudication. Journal of Vascular Surgery. 2011;54:1511.
DS01052 Jan. 20, 2012

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