close window
Housecall Archives
About our e-newsletters
- Free e-newsletters
- Mayo Clinic expertise
- We do not share your e-mail address
Housecall, our weekly general-interest e-newsletter, keeps you up to date on a wide variety of health topics with timely, reliable, practical information, recipes, blogs, questions and answers with Mayo Clinic experts and more. Our biweekly topic-specific e-newsletters also include blogs, questions and answers with Mayo Clinic experts, and other useful information that will help you manage your health.
Housecall Archives
close window
Mayo Clinic Housecall
Stay up to date on the latest health information.
What you get
- Free weekly e-newsletter
- Mayo Clinic expertise
- Recipes, tools and other helpful information
- We do not share your e-mail address
Risk factors
By Mayo Clinic staffSeveral factors may increase the likelihood of a baby developing a cleft lip and cleft palate.
- Family history. Parents with a family history of cleft lip or cleft palate face a higher risk of having a baby with a cleft.
- Race. Cleft lip and palate are most common in American Indian and Asian children. Black children are least likely to have a cleft.
- Sex. Males are twice as likely to have a cleft lip with or without cleft palate. Cleft palate without cleft lip is more common in females.
- Environmental factors. Exposure in early pregnancy to cigarette smoke, alcohol or illicit drugs may put a baby at higher risk of developing a cleft.
- Maternal obesity. Obesity in the mother is associated with a slightly increased risk of cleft lip and palate.
References
- Cleft lip and cleft palate. March of Dimes. http://www.marchofdimes.com/printableArticles/14332_1210.asp. Accessed April 5, 2009.
- Moreau JL, et al. Tissue engineering solutions for cleft palates. Journal of Oral and Maxillofacial Surgery. 2007;65:2503.
- Cleft lip and palate repair. American Society of Plastic Surgeons. www1.plasticsurgery.org/ebusiness4/ProductCatalog/pdf/brochures/Cleft_Lip.pdf. Accessed April 5, 2010.
- Mossey PA, et al. Cleft lip and palate. The Lancet. 2009;374:1773.
- Hoffman WY. Cleft Lip & Palate. In: Lalwani AK. Current Diagnosis & Treatment in Otolaryngology — Head & Neck Surgery. 2nd ed. New York, N.Y.: McGraw-Hill; 2008. http://www.accessmedicine.com/content.aspx?aID=2826340&searchStr=cleft+lip#2826340. Accessed April 5, 2010.
- Craniofacial abnormalities. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/see19/ch288/ch288d.html. Accessed April 5, 2010.
- Burns JL. Plastic surgery (cleft lip and palate). In: Townsend CM Jr, et al. Sabiston Textbook of Surgery. 18th ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/1932697333/978681486/1565/708.html#4-u1.0-B978-1-4160-3675-3..50077-0--cesec9_4303. Accessed April 5, 2010.
- Wilkins-Haug L. Prenatal diagnosis of orofacial clefts. http://www.uptodate.com/home/index.html. Accessed April 5, 2010.
- Stothard KJ, et al. Maternal overweight and obesity and the risk of congenital anomalies: A systematic review and meta-analysis. JAMA. 2009;301:636.
- The school years: An introduction to psychology. Cleft Lip & Palate Association. http://www.clapa.com/news/article/901/. Accessed April 9, 2010.
Find Mayo Clinic on