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Risk factors

By Mayo Clinic staff

Risk factors for cluster headaches include:

  • Gender. Men are more likely to have cluster headaches.
  • Age. Most people with cluster headaches first develop the disorder in their late 20s, although the condition can develop at any age.
  • Smoking. Many people who get cluster headache attacks are smokers.
  • Alcohol use. Alcohol can trigger an attack if you're at risk of cluster headache.
  • A family history. If a parent or sibling has ever had a cluster headache, you may have an increased risk of cluster headaches.
References
  1. Simon RP, et al. Headache and facial pain. In: Simon RP, et al. Clinical Neurology. 7th ed. New York, N.Y.: The McGraw-Hill Companies: 2009. http://www.accessmedicine.com/content.aspx?aID=5146135&searchStr=cluster+headache. Accessed Nov. 24, 2010.
  2. Ropper AH, et al. Headache and other craniofacial pains. In: Ropper AH, et al. Adam's and Victor's Principles of Neurology. 9th ed. New York, N.Y.: The McGraw-Hill Companies; 2009. http://www.accessmedicine.com/content.aspx?aID=3631051&searchStr=cluster+headache. Accessed Nov. 24, 2010.
  3. Goadsby PJ, et al. Headache. In: Fauci AS, et al. Harrison's Online. 17th ed. New York, N.Y.: The McGraw-Hill Companies; 2008. http://www.accessmedicine.com/content.aspx?aID=2890458&searchStr=cluster+headache#2890458. Accessed Nov. 24, 2010.
  4. May A. Cluster headache: Epidemiology, clinical features and diagnosis. http://www.uptodate.com/home/index.html. Accessed Nov. 24, 2010.
  5. Cluster headaches. National Headache Foundation. http://www.headaches.org/education/Headache_Topic_Sheets/Cluster_Headaches. Accessed Nov. 24, 2010.
  6. Headache: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/headache/detail_headache.htm. Accessed Nov. 29, 2010.
  7. Evers S. Pharmacotherapy of cluster headache. Expert Opinion on Pharmacotherapy. 2010;11:2121.
  8. May A. Cluster headache: Acute and preventive treatment. http://www.uptodate.com/home/index.html. Accessed Nov. 24, 2010.
  9. Cohen AS, et al. High-flow oxygen for treatment of cluster headache: A randomized trial. 2009;302:2451.
  10. Francis GJ, et al. Acute and preventive treatment of cluster headache. Neurology. 2010;75:463.
  11. Melatonin. Natural Medicines Comprehensive Database. http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=MAYO&s=ND&pt=100&id=940&ds=&name=MELATONIN&searchid=23998947. Accessed Nov. 23, 2010.
  12. Paemeleire K, et al. Occipital nerve stimulation for headache disorders. Neurotherapeutics: The Journal of the American Society for Experimental Neurotherapeutics. 2010;7:213.
  13. Sewell RA. Response of cluster headache to kudzu. Headache. 2009;49:98.
  14. Rossi P, et al. Use of complementary and alternative medicine by patients with cluster headache: Results of a multi-centre headache clinic survey. Complementary Therapies in Medicine 2008;16:220.
  15. Capsicum. Natural Medicines Comprehensive Database. http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=MAYO&s=ND&pt=100&id=945&ds=&name=CAPSICUM&searchid=23998947. Accessed Nov. 29, 2010.
  16. Swanson JW (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 1, 2010.
  17. Headache diary. National Headache Foundation. http://www.headaches.org/pdf/Headache_Diary.pdf. Accessed Nov. 30, 2010.
DS00487 Feb. 8, 2011

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