Cytomegalovirus (CMV) infection

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Definition

By Mayo Clinic staff

Cytomegalovirus (CMV) is a common virus that can infect almost anyone. Most people don't know they have CMV because it rarely causes symptoms. However, if you're pregnant or have a weakened immune system, CMV is cause for concern.

Once infected with CMV, your body retains the virus for life. However, CMV usually remains dormant if you're healthy. CMV spreads through body fluids, such as blood, saliva, urine, semen and breast milk. People with weak immune systems have a greater risk of becoming ill from CMV. If you're pregnant and develop an active infection, you can pass the virus to your baby.

There's no cure for CMV, but drugs can help treat newborns and people with weak immune systems.

References
  1. Cytomegalovirus (CMV) and congenital CMV infection. Centers for Disease Control and Prevention. http://www.cdc.gov/cmv/overview.html. Accessed March 10, 2011.
  2. Demmler GJ, et al. Cytomegalovirus infection and disease in newborns, infants, children and adolescents. http://www.uptodate.com/home/index.html. Accessed March 3, 2011.
  3. Neurological consequences of cytomegalovirus infection information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/cytomegalic/cytomegalic.htm. Accessed March 10, 2011.
  4. Friel TJ. Epidemiology, clinical manifestations and treatment of cytomegalovirus infection in immunocompetent hosts. http://www.uptodate.com/home/index.html. Accessed March 3, 2011.
  5. Dropulic LK, et al. Update on new antivirals under development for the treatment of double-stranded DNA virus infections. Clinical Pharmacology & Therapeutics. 2010;88:610.
  6. Hirsch MS. Cytomegalovirus and human herpesvirus types 6, 7, and 8. In: Fauci AS, et al. Harrison's Online. 17th ed. 2010. New York, N.Y.: McGraw Hill Companies. http://www.accessmedicine.com/content.aspx?aID=2869361. Accessed March 10, 20111.
DS00938 April 30, 2011

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