Coenzyme Q10: Can it prevent statin side effects?

Is it true that coenzyme Q10 can reduce the risk of serious side effects from statin medications?

- No name / No state given

Mayo Clinic cardiologist Gerald Gau, M.D., and colleagues answer select questions from readers.

Answer

The use of coenzyme Q10 to prevent adverse effects from statin medications is controversial.

Coenzyme Q10 is a substance made naturally by your body. There is some evidence that supplementation with coenzyme Q10 may reduce the risk of serious muscle damage (rhabdomyolysis) — as well as other troubling side effects — from statins. However, no large studies have confirmed this theory, and current guidelines do not recommend routine use of coenzyme Q10 in people taking statins.

Coenzyme Q10 is generally well-tolerated and safe in most people. However, as with other herbal and dietary supplements, it is not regulated by the Food and Drug Administration.

At this time, coenzyme Q10 is not recommended for preventing statin side effects. If you experience muscle aching or other troubling symptoms after starting statin medications, consult your doctor for evaluation. Statins are very beneficial medications for many people, and it's important to do everything possible to continue taking them as directed.