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Risk factors
By Mayo Clinic staffThe use of certain medications has been linked to a higher risk of collagenous colitis and lymphocytic colitis in some people, but this association is unproved. The implicated medications include nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen (Advil, Motrin, others).
Other medications that are associated with an increased risk of collagenous colitis and lymphocytic colitis include the proton pump inhibitor called lansoprazole (Prevacid), the selective serotonin reuptake inhibitor called sertraline (Zoloft), the anti-platelet medication called ticlopidine (Ticlid), the H-2-receptor blocker called ranitidine (Zantac), and the type 2 diabetes medication called acarbose (Precose).
Be sure to tell your doctor about all the medications that you're taking, especially any you began taking in the months before the onset of your diarrhea.
- Collagenous Colitis and Lymphocytic Colitis. National Digestive Diseases Information Clearinghouse. http://digestive.niddk.nih.gov/ddiseases/pubs/collagenouscolitis/. Accessed Aug. 12, 2008.
- Collagenous Colitis and Lymphocytic Colitis. Merck Manual. http://www.merck.com/mmhe/sec09/ch126/ch126d.html. Accessed Aug. 12, 2008.
- Dietrich CF. Lymphocytic and collagenous colitis (microscopic colitis). http://www.uptodate.com/patients/content/topic.do?topicKey=inflambd/5666. Accessed Aug. 12, 2008.
- Wall, Geoffrey C. Pharmacotherapy for Microscopic Colitis. Pharmacotherapy. 2007;27(3):425-433.http://www.medscape.com/viewarticle/555432_1. Accessed Aug. 12, 2008.
- Colitis: A cause of persistent diarrhea in older adults. Mayo Clinic Health Letter.Vol. 25, No. 3, March 2007.
- Antidiarrheal Medicines: OTC Relief for Diarrhea. American Academy of Family Physicians. http://familydoctor.org/online/famdocen/home/otc-center/otc-medicines/855.html#ArticleParsysMiddleColumn0010. Accessed Aug. 12, 2008.
