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  • With Mayo Clinic internist

    Brent A. Bauer, M.D.

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Question

Colloidal silver: Is it safe or effective?

My dad takes colloidal silver for his health, but is it safe?

Answer

from Brent A. Bauer, M.D.

Colloidal silver isn't considered safe or effective for any of the health claims manufacturers make. Silver has no known purpose in the body. Nor is it an essential mineral, as some sellers of silver products claim.

Colloidal silver products are made of tiny silver particles suspended in a liquid — the same type of precious metal used in jewelry, dental fillings, silverware and other consumer goods. Colloidal silver products are usually marketed as dietary supplements that are taken by mouth. Colloidal silver products also come in forms to be injected or applied to the skin.

Manufacturers of colloidal silver products often claim that they are cure-alls, boosting your immune system, fighting bacteria and viruses, and treating cancer, HIV/AIDS, shingles, herpes, eye ailments and prostatitis. However, no sound scientific studies to evaluate these health claims have been published in reputable medical journals. In fact, the Food and Drug Administration has taken action against some manufacturers of colloidal silver products for making unproven health claims.

It's not clear how much colloidal silver may be harmful, but it can build up in your body's tissues over months or years. Most commonly, this results in argyria (ahr-JIR-e-uh), a blue-gray discoloration of your skin, eyes, internal organs, nails and gums. While argyria doesn't pose a serious health problem, it can be a cosmetic concern because it doesn't go away when you stop taking silver products.

Rarely, excessive doses of colloidal silver can cause possibly irreversible serious health problems, including kidney damage and neurological problems such as seizures. Colloidal silver products may also interact with medications, including penicillamine, quinolone, tetracycline and thyroxine medications.

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References
  1. Colloidal silver products. National Center for Complementary and Alternative Medicine. http://nccam.nih.gov/health/silver/. Accessed June 10, 2011.
  2. Mayr M, et al. Argyria and decreased kidney function: Are silver compounds toxic to
  3. the kidney? American Journal of Kidney Diseases. 2009;5:890.
  4. Kim Y, et al. A case of generalized argyria after ingestion of colloidal silver solution. American Journal of Industrial Medicine. 2009;52:246.
  5. Fung M., et al. Colloidal silver proteins marketed as health supplements. Journal of the American Medical Association. 1995;15:1196.
  6. Mirsattari SM, et al. Myoclonic status epilepticus following repeated oral ingestion of colloidal silver. Neurology. 2004;62:1408.
  7. Over-the-counter drug products containing colloidal silver ingredients or silver salts. U.S. Food and Drug Administration. http://www.fda.gov/ohrms/dockets/98fr/081799a.txt. Accessed June 10, 2011.
  8. Colloidal silver. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed June 10, 2011.
  9. Bauer BA (expert opinion). Mayo Clinic, Rochester, Minn. June 10, 2011.
AN01682 Sept. 3, 2011

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