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Treatments and drugs

By Mayo Clinic staff

Coma is a medical emergency, and attention first is given to maintaining respiration and circulation. Assistance with breathing, administration of fluids and blood, and other supportive care may be necessary.

Emergency personnel may administer glucose or antibiotics intravenously, even before blood test results return, on the chance that the person is in diabetic shock or has an infection affecting the brain.

Treatment varies, depending on what's causing the coma. Sometimes surgery is needed to relieve the pressure due to brain swelling. Other treatments may focus on addressing an underlying disease, such as diabetes, kidney failure or liver disease.

Sometimes the cause of coma can be completely reversed and the person will regain normal function. But if the brain damage is severe, the person may sustain permanent disabilities or may never regain consciousness.

References
  1. Berger JR. Stupor and coma. In: Bradley. Neurology in Clinical Practice. 5th ed. Burlington, Mass.: Butterworth-Heinemann; 2008. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-0-7506-7525-3..50007-8--cesec4&uniq=189705338&isbn=978-0-7506-7525-3&sid=969544059. Accessed March 18, 2010.
  2. Simon RP. Coma and disorders of arousal. In: Goldman L, et al., eds. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/189705338-11/969548074/1492/1435.html#4-u1.0-B978-1-4160-2805-5..50433-X--cesec2_18138. Accessed March 18, 2010.
  3. Young BG. Stupor and coma in adults. http://www.uptodate.com/home/index.html. Accessed March 18, 2010.
  4. Cooke JL. Depressed consciousness and coma. In: Marx JA, et al., eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 6th ed. St. Louis, Mo.: Mosby; 2006. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-0-323-05472-0..00014-1&uniq=189705338&isbn=978-0-323-05472-0&sid=969548074#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-0-323-05472-0..00014-1%3Bfrom%3Dtoc%3Btype%3DbookPage%3Bisbn%3D978-0-323-05472-0. Accessed March 18, 2010.
  5. Wijdicks EF (expert opinion). Mayo Clinic, Rochester, Minn. March 23, 2010.
DS00724 May 8, 2010

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