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  • With Mayo Clinic diabetes educators

    Nancy Klobassa Davidson, R.N., and Peggy Moreland, R.N.

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  • Living with diabetes blog

  • April 3, 2013

    Stress, illness and high blood sugar

    By Nancy Klobassa Davidson, R.N., and Peggy Moreland, R.N.

65 comments posted

Controlling Your Diabetes

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A number of you have mentioned that your blood sugar runs higher when you are ill or under stress.

Illness or stress can trigger high blood sugars because hormones produced to combat illness or stress can also cause your blood sugar to rise.

People who do not have diabetes can make enough extra insulin to keep their blood sugar in a normal range during times of stress and illness. People with diabetes may need to take extra diabetes medication to keep their blood sugar near normal during times of illness or stress. If you haven't been given special instructions on how to manage your diabetes medications during illness, please contact your healthcare provider for advice.

Sometimes you may need to be a detective. Here are some possible causes of high blood sugars:

  • Not enough insulin or oral diabetes medication
  • Eating or drinking more carbohydrate than usual
  • Less activity or exercise than usual
  • Illness or infection (cold, urinary tract infection, heart attack)
  • Injury or surgery
  • Pain
  • Positive stress (wedding or vacation) or negative stress (a death in the family)
  • Any change in your normal daily routine
  • Certain medications
  • Poor absorption of insulin at injection sites
  • Insulin pump, insulin pen or meter (device issues)
  • Bad insulin (outdated insulin or insulin that has been exposed to extreme temperatures)

In rare incidences, stress can cause blood sugars to drop low.

Make sure you know the symptoms of high blood sugar.

Early signs/symptoms Later signs/symptoms
Increased thirst Fruity-smelling breath
Increased urination Nausea and/or vomiting
Fatigue Abdominal pain
Blurred vision Rapid breathing
  Weakness
  Confusion
  Unconsciousness

When to contact your healthcare provider:

  • You notice symptoms of high blood sugars
  • Ongoing diarrhea or vomiting for more than 24 hours — or sooner if you're becoming dehydrated
  • Fever that lasts more than 24 hours
  • Blood sugar readings greater than 250 mg/dl (13.9 mmol/L) for more than 24 hours during illness
  • If you have been instructed to check urine ketones and they are present (type 1 diabetes)

Call the emergency department if you experience any of the later signs and symptoms of high blood sugar.

Please share your experiences. Thanks.

- Nancy

65 comments posted

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  • May 23, 2013 6:50 p.m.

    We should learn to reduce or control our food intake so that we do not come to the situation where we are unable to enjoy the various food available in the menu. Good knowledge to gain so read on. http://wellnesshealthproduct.com/blog/

    - Amir

  • May 5, 2013 11:02 p.m.

    I have PTSD, anxiety, depression, panic attacks (that can last as long as 40 minutes). I know stress causes high blood sugar. What can I do? I have 3-5 episodes per day. Doctors I talk to don't understand the hormones released during these attacks and just treat the high sugar. Is there more that can be done?

    - sly288

  • April 16, 2013 2:51 p.m.

    Arlayne, Wow fibromyalgia and type 1 diabetes!I would see your provider about setting up a rapid insulin correction scale to cover your blood glucoses the days that the fibromalgia pain elevates the blood glucoses.

    - Nancy and Peggy

  • April 16, 2013 1:30 p.m.

    T2 and quit Metformin. Some people are not able to tolerate the gastro intestinal side effects of Metformin and need to quit taking it. Please talk with your provider about other diabetes mediations that do not have the GI side effects. Take care.

    - Nancy and Peggy

  • April 15, 2013 12:53 p.m.

    What a kind, helpful & intelligent comment from Jennae to Holly. Holly, Jennae is giving you exactly the right advice. Reach out! You're not alone -- and we never have to be alone with all the help that is available to us Type 2's. It's a very very tough disease to accept and to deal with. But you can do it. I, too, suffer from clinical depression and Type 2. My blood sugars were over 500! For the longest time! But now, with medication, lots of effort, and my great medidal team behind me, I average 124. That's a life-changing number, believe me....and I want that for you, too. Call today -- ask for a nurse practitioner or a diabetic educator. You'll never regret reaching out. Good luck -- you're in my prayers, Holly.

    - Linda

  • April 10, 2013 1:56 p.m.

    I'm a T2 and quit taking metformin due to constant diarrhea, bloating and cramps. Am I alone??

    - tracy

  • April 9, 2013 1:14 p.m.

    @Holly Holly, you need to seek real help, not post and hope. Sticking your head in the sand is not an unusual response to newly diagnosed diabetes, but it sure is an unhealthy one. Make the call today to get psychological support and to see a nurse specialist that can take time to guide and check in on you. Most of us Type 2's dug our own hole with overeating,true, but the wonderful thing is, we can use our diabetes as a most wonderful motivator to change our lives. Your depression is too heavy to handle alone. I hear you and hope you have a primary care doctor to call for a referral. If not, please do call your local 211 assistance line or see your pastor if possible. Without a change, you are simply committing a very slow and unpleasant suicide. Please don't. Please take a positive action today for yourself.

    - Jennae

  • April 9, 2013 12:29 p.m.

    Arlayne Did your Dr. inform you that stress and pain can also play apart why your blood sugars my be high? You mention you have Fibromyalgia that may be causing the pike in your blood sugars. Keep watch of your diet,excerise if you can. Hormones can also increase blood sugars .

    - m.j

  • April 9, 2013 12:20 p.m.

    Be patient. The first year is the hardest . Watch what you eat and measure your carb intakes. Rice,breads,potatoes will pike up your blood sugars. Excerise helps lower blood sugars. If you are able to do some walking daily and you will see results .

    - m.j

  • April 9, 2013 11:21 a.m.

    I am a newly diagnosed Type 1 diabetic and I'm still trying to get my A1C 10.9 down. I also have fibromyalgia and it is very dibilitating when I have a flareup, which started about 2 weeks ago. My sugar levels have been fluctuating between 140-300, which is higher than my doctor wants it to be. Does anyone have any suggestions on how I can counteract higher levels during a flareup?

    - Arlayne

  • December 10, 2012 8:16 a.m.

    I have Cramp Fasciculation Syndrome and since the symptoms have developed my blood sugar has risen. I have type 2 diabetes which was previously in excellent control. Now that has changed from my illness.

    - Margie

  • December 5, 2012 5:19 p.m.

    CGM and stable state. It appears to me that this new feature does a good job of monitoring your levels as look as your in a tightly controlled range. But if I see 140 on my read out I may be 270 and if I go low it also seems to loss range moving away from what my actual B/S is. As a long time type One the information I need is mainly when I am out of range. Maybe the Engineers forgot that. I am using the new CGM more to show direction shifts and increasing my basal/or bolus if I see a move up above 130. Don't get me wrong this is a great improvement from urine testing. Any thought?

    - Billum

  • November 6, 2012 1:36 p.m.

    I have had type 1 diabetes for 43 years and avg 7.8 A1c..feel I am moderately controlled under the circumstances blood sugars usually between 70-200. I am on an insulin pump and recently have had some unusually high blood sugars 3 of the last 4 evenings even though I have not done anything...eating..exercise, stress out of the normal. I normally take about 43 units a day but on these evenings I have had to take an extra 30 units to get me out of these high readings and it seems like it takes forever-5 to 8 hours. they start out at 375 and when I take a bolus they go up 50-75 and then another bolus and go up slightly higher to 500 or maintain their high levels in the high 400s for 5 -8 hours. I have switched pump sites, changed insulin bottles and even injected insulin twice in my leg with a syringe but it still takes 5-8 hours before they come down below 200. Any thoughts on what might be occuring or tests I should consider taking to determine what is causing this? Appreciate any insight you might have into this puzzling and unusual occurrence for me.

    - John

  • July 19, 2012 1:22 p.m.

    Counter-regulatory hormones in the body react to stress and raise the blood glucose.

    - Nancy and Peggy

  • July 13, 2012 8:44 p.m.

    I have been a type II Diabetic for two years. Just lately my reading have been running higher and higher. Mornings could be 148 and 156 but I was having at leastt lower readings during the day, like 120 or so. Now I took my sugar tonight and it's 199. Yes I have had quite a few health issues since it's started. Two knee replacements, a revision of one, an artery nicked during the replacemnt. Now on my second hand operation of carpol tunnel. I never really without pain, so how can my sugars go down. Just thinking about it going up, I think makes it go up.

    - Jo-Ann

  • July 8, 2012 8:14 a.m.

    I take my readings 5 to 7 times daily. Some weeks my readings at morning fasting are 95 to 115. Other weeks they are at 120 to 130. I am prediabetic and take metformin. Why the big difference? I don't eat anything differently and exercise everyday. Jog 1 to 3 miles daily.

    - Steve

  • June 7, 2012 7:26 p.m.

    thanks for your help sugars are running in the 300-350 A1c is 7.6 there is a great deal of stress have lost 6lb in 4 weeks

    - sue

  • June 1, 2012 6:14 a.m.

    Thanks for the info Nancy, I had a back injury on monday and after running 60-110s for the past year with my A1c going to 5.1, I am now running 250 and above...going to MD today !!

    - Mary

  • May 21, 2012 7:55 p.m.

    525 sugar this AM. Wondered what the cause of such a spike could be and how dangerous . It is down to 200 now.

    - Jerry

  • April 18, 2012 8:13 a.m.

    Yes, pain can raise the blood glucose.

    - Nancy and Peggy

  • April 13, 2012 6:08 p.m.

    i am having severe pain from a torn rotor cuff and will most likely have to have surgery and now for the past week my sugar has been holding between 160 and 275. is stress causing this priblem?p5MLRq

    - ruth

  • February 18, 2012 10:21 a.m.

    Thank you so much for the info I been diabetic for over 12 years and recently got a head cold.Well to make long story short my blood sugars have sometimes been over 400 since I got the head cold.I know now that it must be this cold that is causing my high blood sugars.Cause I always take my meds and insulin.

    - Ray

  • February 12, 2012 11:24 p.m.

    I have type two diabeties and a lot of stress. The stress is multiplied by my birth daughter who just told my boyfriend's family that he is a druggy and used to have sex with underage girls. These are all lies but the damage is done and now I just want to crawl in a hole and die. I have prayed and asked for help but so far nothing and the pain of everything is too much for me. I just took my shot an hour ago and my blood sugar is still 261. HO GOD HELP ME PLEASE!!!!!!!!!

    - LaDayna

  • January 9, 2012 4:06 p.m.

    I have been diagnosed with type2 diabetes and depression. I am having a hard time with the fact I am insulin dependant and not taking my injections when I should. My blood sugars in the am have all been over 300 sometimes spiking to 420 or so, should I contact my physician or ER when this occurs for more than a week?

    - holly

  • January 2, 2012 9:10 p.m.

    I am a 65 y/o woman with Type 2 diabetes. I have been very ill for the last month with an infection that affected my sinuses, throat and lungs. Being unusually ill, I saw a lung specialist who informed me, after examination, that I am as sick as I am because I also have intermittent asthma. I am on antibiotics and Spiriva (5th day) and my question is this: My sugars are in the 180-250 range, in spite of the fact that I am only consuming about 24-36 gm. of good carbohydrates, per meal. I take 2000 mg. Metformin, 100 mg Januvia, 20 mg. Glipizide and 2500 mg. Welchol, per day (in addition to other drugs and supplements). Should I be concerned about the levels of glucose? Or, should I just keep monitoring my numbers, 2-3X per day? What's normal, considering I'm so sick? Thank you!

    - Nikki

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