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Definition

By Mayo Clinic staff

Chronic obstructive pulmonary disease (COPD) refers to a group of lung diseases that block airflow and make breathing difficult.

Emphysema and chronic bronchitis are the two most common conditions that make up COPD. Chronic bronchitis is an inflammation of the lining of your bronchial tubes, which carry air to and from your lungs. Emphysema occurs when the air sacs (alveoli) at the end of the smallest air passages (bronchioles) in the lungs are gradually destroyed.

Damage to your lungs from COPD can't be reversed, but treatment can help control symptoms and minimize further damage.

References
  1. Balkissoon R, et al. Chronic obstructive pulmonary disease: A concise review. Medical Clinics of North America. 2011;95:1125.
  2. Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Dec. 2, 2012.
  3. What is chronic obstructive pulmonary disease? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/copd/printall-index.html. Accessed Dec. 2, 2012.
  4. Standards for the diagnosis and management of patients with COPD. American Thoracic Society. http://www.thoracic.org/clinical/copd-guidelines/index.php. Accessed Dec. 2, 2012.
  5. Hanley ME, et al. Current Diagnosis & Treatment in Pulmonary Medicine. New York, N.Y.: The McGraw-Hill Companies; 2003. http://www.accessmedicine.com/content.aspx?aID=575706. Accessed December 2, 2012.
  6. Foreman MG. Genes and chronic obstructive pulmonary disease. Medical Clinics of North America. 2012;96:699.
  7. Rosenberg SR, et al. An integrated approach to the medical treatment of chronic obstructive pulmonary disease. Medical Clinics of North America. 2012;96:811.
  8. Scanlon PD (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 27, 2012.
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