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Definition

By Mayo Clinic staff

Coronary artery disease develops when your coronary arteries — the major blood vessels that supply your heart with blood, oxygen and nutrients — become damaged or diseased. Cholesterol-containing deposits (plaques) on your arteries are usually to blame for coronary artery disease.

When plaques build up, they narrow your coronary arteries, causing your heart to receive less blood. Eventually, diminished blood flow may cause chest pain (angina), shortness of breath or other coronary artery disease symptoms. A complete blockage can cause a heart attack.

Because coronary artery disease often develops over decades, it can go virtually unnoticed until it produces a heart attack. But there's plenty you can do to prevent and treat coronary artery disease. Start by committing to a healthy lifestyle.

References
  1. Coronary artery disease. National Lung, Heart, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/Cad/CAD_WhatIs.html. Accessed April 29, 2010.
  2. Morrow DA, et al. Chronic coronary artery disease. In: Libby P, et al., eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-1-4160-4106-1..50057-1&uniq=198193047&isbn=978-1-4160-4106-1&sid=989729689. Accessed April 29, 2010.
  3. Toth PP, et al. Coronary artery disease. In: Rakel RE. Rakel: Textbook of Family Medicine. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/198193047-17/0/1481/455.html#4-u1.0-B978-1-4160-2467-5..50041-5--cesec46_2228. Accessed April 29, 2010.
  4. Hall SL, et al. Secondary prevention of coronary artery disease. American Family Physician. 2010;81:289.
  5. Wilson PWF. Overview of the risk factors for cardiovascular disease. http://www.uptodate.com/home/index.html. Accessed April 29, 2010.
  6. Body composition tests. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4489. Accessed April 29, 2010.
  7. Heart disease. National Center for Complementary and Alternative Medicine. http://nccam.nih.gov/health/heart-disease/. Accessed April 29, 2010.
  8. Grogan M (expert opinion). Mayo Clinic, Rochester, Minn. May 7, 2010.
  9. Lovett E, et al. Advising patients about herbs and nutraceuticals: Tips for primary care providers. Primary Care: Clinics in Office Practice. 2010;37:13.
DS00064 July 2, 2010

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