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By Mayo Clinic staffLimited scleroderma, or CREST syndrome, is one subtype of scleroderma — a condition that literally means "hardened skin."
The skin changes associated with limited scleroderma typically occur only in the lower arms and legs, and sometimes the face and throat. Limited scleroderma can also affect your digestive tract and can cause serious heart and lung disorders.
For some people, the problems caused by limited scleroderma are minor. For others, limited scleroderma can be life altering and even fatal. The disease has no known cure, and treatments focus on managing symptoms and preventing serious complications.
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