Creutzfeldt-Jakob disease

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Complications

By Mayo Clinic staff

As with other causes of dementia, Creutzfeldt-Jakob disease profoundly affects the mind as well as the body, although CJD and its variants usually progress much more rapidly. People with CJD usually withdraw from friends and family and eventually lose the ability to recognize or relate to them in any meaningful way. They also lose the ability to care for themselves, and many eventually slip into a coma. The disease ultimately is fatal.

Physical complications, all of which may become life-threatening, include:

  • Infection
  • Heart failure
  • Respiratory failure
References
  1. Creutzfeldt-Jakob disease and other prion diseases. Creutzfeldt-Jakob Disease Foundation. http://www.cjdfoundation.org/documents/aboutcjd.pdf. Accessed March 24, 2010.
  2. Creutzfeldt-Jakob disease fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/cjd/detail_cjd.htm. Accessed March 24, 2010.
  3. Brown HG, et al. Creutzfeldt-Jakob disease. http://www.uptodate.com. Accessed March 24, 2010.
  4. Brown HG, et al. Variant Creutzfeldt-Jakob disease. http://www.uptodate.com. Accessed March 25, 2010.
  5. vCJD (variant Creutzfeldt-Jakob disease). Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dvrd/vcjd/factsheet_nvcjd.htm. Accessed March 24, 2010.
  6. CJD fact sheet. Creuzfeldt-Jakob Disease Foundation Inc. http://www.cjdfoundation.org/. Accessed March 24, 2010.
  7. vCJD (Variant Creutzfeldt-Jakob disease): Risk for travelers. Centers for Disease Control and Prevention.  http://www.cdc.gov/ncidod/dvrd/vcjd/risk_travelers.htm. Accessed March 24, 2010.
DS00531 May 14, 2010

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