Cryptosporidium infection

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Tests and diagnosis

By Mayo Clinic staff

You may undergo the following tests to diagnose cryptosporidium infection:

  • Acid-staining test. The simplest way to diagnose cryptosporidium infection is a method called an acid-staining test, which identifies cryptosporidium under a microscope. To obtain cells for the analysis, your doctor might ask for a stool sample, or in more extreme cases, take a tissue sample (biopsy) from your intestine for the test.
  • Stool culture. Your doctor might also order a standard stool culture. Although this test cannot detect the presence of cryptosporidium, it may help rule out other bacterial pathogens.
  • Other tests. Once it's clear that your infection is cryptosporidium, you may need further testing to check for development of serious complications. For example, checking liver and gallbladder function may determine whether the infection has spread.

    If you have both AIDS and cryptosporidiosis, a T cell count — which measures the level of a certain white blood cell that's part of your immune system — can help predict the duration of the cryptosporidiosis. A high T cell count means you're more likely to recover quickly, while a low count means you may need to be monitored for further complications.

References
  1. Cryptosporidiosis: Disease. Centers for Disease Control and Prevention. http://www.cdc.gov/parasites/crypto/disease.html. Accessed Jan. 24, 2011.
  2. Leder K, et al. Cryptosporidiosis. http://www.uptodate.com/home/index.html. Accessed Jan. 24, 2011.
  3. Cryptosporidiosis: Infection - General public. Centers for Disease Control and Prevention. http://www.cdc.gov/parasites/crypto/gen_info/infect.html. Accessed Jan. 24, 2011.
  4. Cryptosporidiosis: Prevention - General public. Centers for Disease Control and Prevention. http://www.cdc.gov/parasites/crypto/gen_info/prevent.html. Accessed Jan. 24, 2011.
  5. Bad bug book: Foodborne pathogenic microorganisms and natural toxins handbook — Cryptosporidium parvum. U.S. Food and Drug Administration. http://www.fda.gov/Food/FoodSafety/FoodborneIllness/FoodborneIllnessFoodbornePathogensNaturalToxins/BadBugBook/ucm070753.htm. Accessed. Jan. 24, 2011.
  6. Cryptosporidiosis: Epidemiology & risk factors. Centers for Disease Control and Prevention. http://www.cdc.gov/parasites/crypto/epi.html. Accessed Jan. 24, 2011.
  7. Rosenthal PJ. Protozoal & helminthic infections. In: McPhee SJ, et al. Current Medical Diagnosis & Treatment 2011. 50th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/content.aspx?aID=778396. Accessed Jan. 25, 2011.
  8. Kirkpatrick BD, et al. Cryptosporidiosis. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Jan. 25, 2011.
DS00907 March 4, 2011

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