Cushing's syndrome

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Symptoms

By Mayo Clinic staff

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Image showing Cushing's syndrome 
Cushing's syndrome

Common Cushing's syndrome symptoms include:

  • Weight gain, particularly around your midsection and upper back
  • Fatigue
  • Muscle weakness
  • Rounding of your face (moon face)
  • Facial flushing
  • Fatty pad or hump between your shoulders (buffalo hump)
  • Pink or purple stretch marks (striae) on the skin of your abdomen, thighs, breasts and arms
  • Thin and fragile skin that bruises easily
  • Slow healing of cuts, insect bites and infections
  • Depression, anxiety and irritability
  • Loss of emotional control
  • Thicker or more visible body and facial hair (hirsutism)
  • Acne
  • Irregular or absent menstrual periods in females
  • Decreased libido
  • Erectile dysfunction in males
  • New or worsened high blood pressure
  • Glucose intolerance that may lead to diabetes
  • Headache
  • Bone loss, leading to fractures over time

When to see a doctor
If you're taking corticosteroid medications to treat a condition, such as asthma, arthritis or inflammatory bowel disease, and experience signs and symptoms that may indicate Cushing's syndrome, see your doctor for an evaluation. Even if you're not using these drugs and you have symptoms that suggest the possible presence of Cushing's syndrome, contact your doctor.

DS00470

Sept. 12, 2008

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