Cytochrome P450 (CYP450) genotyping test

Mayo Clinic Health Manager

Get free personalized health guidance for you and your family.

Get Started

Free

E-Newsletter

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Definition

By Mayo Clinic staff

The cytochrome P450 genotyping test (CYP450 test) predicts how your body will process (metabolize) certain antidepressants. The CYP450 test is one of the newer entries in the emerging field of pharmacogenomics, or personalized medicine.

Before the CYP450 test, doctors had little way of knowing how you would respond to a particular antidepressant — whether you would develop troubling side effects, for instance, or whether the medication would even be of benefit. By analyzing how specific genes in your liver break down medications, the CYP450 test may remove some of the guesswork.

The CYP450 test isn't yet widely available. But as genotyping tests such as CYP450 become more well-known, they may offer better options for the treatment of depression.

MY00135

May 30, 2008

© 1998-2009 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Reliable tools for healthier lives," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Text Size: smaller largerlarger