Cytochrome P450 (CYP450) tests

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How you prepare

By Mayo Clinic staff

You won't need to fast or have any special preparations before the procedure.

References
  1. Mrazek DA. Psychiatric pharmacogenomic testing in clinical practice. Dialogues in Clinical Neuroscience. 2010;12:69.
  2. Wand L, et al. Genomics and drug response. The New England Journal of Medicine. 2011;364:1144.
  3. Goetz MP. Update on CYP2D6 and its impact on tamoxifen therapy. Clinical Advances in Hematology & Oncology. 2010;8:536.
  4. McAlpine DE, et al. Effect of cytochrome P450 enzyme polymorphisms on pharmacokinetics of venlafaxine. Therapeutic Drug Monitoring. 2011;33:14.
  5. Fleeman N, et al. Cytochrome P450 testing for prescribing antipsychotics in adults with schizophrenia: Systemic review and meta-analysis. The Pharmacogenomics Journal. 2011;11:1.
  6. Genetic testing — CYP450 genotyping to predict response to SSRIs used to treat non-psychotic depression in adults: EGAPP recommendation. Centers for Disease Control and Prevention. http://www.cdc.gov/genomics/gtesting/EGAPP/recommend/CYP450.htm. Accessed Aug. 29, 2012.
  7. Steimer W. Pharmacogenetics and psychoactive drug therapy: Ready for the patient? Therapeutic Drug Monitoring. 2010;32:381.
  8. Mrazek DA, et al. Facilitating clinical implementation of pharmacogenomics. JAMA. 2011:306:304.
  9. Kung S (expert opinion). Mayo Clinic Rochester, Minn. Aug. 15, 2012.
  10. Coumadin (prescribing information). Princeton, N.J.: Bristol-Myers Squibb Company; 2011. http://packageinserts.bms.com/pi/pi_coumadin.pdf. Accessed Aug. 21, 2012.
MY00135 Sept. 7, 2012

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