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Definition

By Mayo Clinic staff

Cystic fibrosis (CF) is a life-threatening disorder that causes severe lung damage and nutritional deficiencies.

An inherited condition, cystic fibrosis affects the cells that produce mucus, sweat, saliva and digestive juices. Normally, these secretions are thin and slippery, but in cystic fibrosis, a defective gene causes them to become thick and sticky. Instead of acting as a lubricant, the secretions plug up tubes, ducts and passageways, especially in the pancreas and lungs.

Respiratory failure is the most dangerous consequence of cystic fibrosis. Also, the secretions block pancreatic enzymes that help digest fats and proteins, and they prevent your body from absorbing key vitamins.

Treatments for cystic fibrosis are aimed at relieving symptoms and complications.

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March 1, 2008

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