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Treatments and drugs
By Mayo Clinic staffCystitis caused by bacterial infection is generally treated with antibiotics. Treatment for noninfectious cystitis depends on the underlying cause.
Treating bacterial cystitis
Antibiotics are the first line of treatment for cystitis caused by bacteria. Which drugs are used and for how long depend on your overall health and the bacteria found in your urine.
- First-time infection. Symptoms often improve significantly within a day or so of antibiotic treatment. However, you'll likely need to take antibiotics for three days to a week, depending on the severity of your infection. No matter what the length of treatment, take the entire course of antibiotics prescribed by your doctor to ensure that the infection is completely gone.
- Repeat infection. If you have recurrent UTIs, your doctor may recommend longer antibiotic treatment or refer you to a doctor who specializes in urinary tract disorders (urologist or nephrologist) for an evaluation, to see if urologic abnormalities may be causing the infections. For some women, taking a single dose of an antibiotic after sexual intercourse may be helpful.
- Hospital-acquired infection. Hospital-acquired bladder infections can be a challenge to treat because bacteria found in hospitals are often resistant to the common types of antibiotics used to treat community-acquired bladder infections. For that reason, different types of antibiotics and different treatment approaches may be needed.
Postmenopausal women may be particularly susceptible to cystitis. As a part of your treatment, your doctor may recommend a vaginal estrogen cream — if you're able to use this medication without increasing your risk of other health problems.
Treating interstitial cystitis
With interstitial cystitis, the cause of inflammation is uncertain, so there's no single treatment that works best for every case. Therapies used to ease the signs and symptoms of interstitial cystitis include:
- Medications that are taken orally or inserted directly into your bladder
- Procedures that manipulate your bladder to improve symptoms, such as stretching the bladder with water or gas (bladder distention) or surgery
- Nerve stimulation, which uses mild electrical pulses to relieve pelvic pain and, in some cases, reduce urinary frequency
Treating other forms of noninfectious cystitis
If you're hypersensitive to certain chemicals in products such as bubble bath or spermicides, avoiding these products may help ease symptoms and help prevent further episodes of cystitis.
Treatment of cystitis that develops as a complication of chemotherapy or radiation therapy focuses on pain management, usually with medications, and hydration to flush out bladder irritants. Most cases of chemotherapy-induced cystitis tend to resolve after the chemotherapy is finished.
- Katz VL, et al. Comprehensive Gynecology. 6th ed. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-323-06986-1..C2009-0-48752-X--TOP&isbn=978-0-323-06986-1&uniqId=325227117-5. Accessed March 22, 2012.
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- Hooton TM. Acute uncomplicated cystitis and pyelonephritis in women. http://www.uptodate.com/index. Accessed March 22, 2012.
- Interstitial cystitis/painful bladder syndrome. National Kidney & Urologic Diseases Information Clearinghouse. http://kidney.niddk.nih.gov/kudiseases/pubs/interstitialcystitis/. Accessed March 22, 2012.
- French L, et al. Urinary problems in women. Primary Care: Clinics in Office Practice. 2009;36:53.
- Hooton TM. Recurrent urinary tract infections in women. http://www.uptodate.com/index. Accessed March 22, 2012.
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- Ferri FF. Ferri's Clinical Advisor 2012: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-323-05611-3..C2009-0-38601-8--TOP&isbn=978-0-323-05611-3&uniqId=291436269-101. Accessed March 26, 2012.
- Brenner BM. Brenner & Rector's The Kidney. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-1-4160-6193-9..C2010-1-67932-1--TOP&isbn=978-1-4160-6193-9&uniqId=321553651-265. Accessed March 26, 2012.
- Tanagho EA, et al. Smith's General Urology. 17th ed. New York, N.Y.: The McGraw-Hill Companies; 2008. http://www.accessmedicine.com/content.aspx?aID=3130813. Accessed March 27, 2012.
- Gupta K, et al. International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Disease Society of America and the European Society for Microbiology and Infectious Diseases. Clinical Infectious Diseases. 2011;52:e103.
- Cranberry. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed March 27, 2012.
- Castle EP (expert opinion). Mayo Clinic, Phoenix, Ariz. April 11, 2012.
- Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed April 4, 2012.
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