Ductal carcinoma in situ (DCIS)

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Risk factors

By Mayo Clinic staff

In general, the factors that put you at risk of developing DCIS are the same as risk factors for developing invasive breast cancer.

Things that increase your risk of DCIS include:

  • Older age
  • Personal history of benign breast disease, such as atypical hyperplasia
  • Family history of breast cancer
  • Never having been pregnant
  • First pregnancy after age 30
  • Taking combination estrogen-progestin hormone replacement therapy (HRT) for five years or longer after menopause.
  • Genetic mutations, such as in the BRCA1 or BRCA2 genes
References
  1. What is breast cancer? American Cancer Society. http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_is_breast_cancer_5.asp?sitearea=. Accessed May 7, 2009.
  2. Lagios MD. Breast ductal carcinoma in situ and microinvasive carcinoma. http://www.uptodate.com/home/index.html. Accessed May 7, 2009.
  3. Meisner ALW, et al. Breast disease: Benign and malignant. Medical Clinics of North America. 2008;92:1115.
  4. Do we know what causes breast cancer? American Cancer Society. http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_Do_we_know_what_causes_breast_cancer_5.asp?rnav=cri. Accessed May 7, 2009.
  5. Costanza ME, et al. Epidemiology and risk factors for breast cancer. http://www.uptodate.com/home/index.html. Accessed May 7, 2009.
  6. The basics of DCIS. Breastcancer.org. http://www.breastcancer.org/symptoms/types/dcis/basics.jsp. Accessed May 7, 2009.
  7. Can breast cancer be found early? American Cancer Society. http://www.cancer.org/docroot/CRI/content/CRI_2_4_3X_Can_breast_cancer_be_found_early_5.asp?rnav=cri. Accessed May 7, 2009.
  8. Hulvat MC, et al. Multidisciplinary care for patients with breast cancer. Surgical Clinics of North America. 2009;89:133.
  9. How is breast cancer treated? American Cancer Society. http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_Treatment_of_stage_0_breast_cancer.asp?rnav=cri. Accessed May 7, 2009.
  10. The emotional impact of a cancer diagnosis. American Cancer Society. http://www.cancer.org/docroot/MBC/content/MBC_4_1X_The_Emotional_Impact_of_A_Cancer_Diagnosis.asp?sitearea=MBC. Accessed May 7, 2009.
  11. What are the risk factors for breast cancer? American Cancer Society. http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_What_are_the_risk_factors_for_breast_cancer_5.asp?rnav=cri. Accessed May 7, 2009.

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Nov. 18, 2009

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