Ductal carcinoma in situ (DCIS)

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Definition

By Mayo Clinic staff

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Illustration of breast, including lymph nodes, lobules and ducts 
Breast anatomy

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Ductal carcinoma in situ (DCIS) is the presence of abnormal cells inside a milk duct in the breast. DCIS is considered the earliest form of breast cancer. DCIS is noninvasive, meaning it hasn't spread out of the milk duct to invade other parts of the breast.

DCIS is usually found during a mammogram done as part of breast cancer screening. Because of increased screening with mammograms, the rate at which DCIS is diagnosed has increased dramatically in recent years.

While DCIS isn't life-threatening, it does require treatment to prevent the condition from becoming invasive. Most women with DCIS are effectively treated with breast-conserving surgery and radiation.

References
  1. Abeloff MD, et al. Cancer of the breast. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2008:1875.
  2. Iglehart JD, et al. Diseases of the breast. In: Townsend CM Jr, et al. Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. 18th ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/208746819-6/0/1565/0.html. Accessed April 15, 2011.
  3. Breast cancer. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/breast.pdf. Accessed April 15, 2011.
  4. Ganz PA. Quality-of-life issues in patients with ductal carcinoma in situ. Journal of the National Cancer Institute Monographs. 2010;41:218.
  5. Deng GE, et al. Evidence-based clinical practice guidelines for integrative oncology: Complementary therapies and botanicals. Journal of the Society for Integrative Oncology. 2009;7:85.
DS00983 June 23, 2011

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