DefinitionBy Mayo Clinic staff
Deep brain stimulation involves implanting electrodes within certain areas of your brain. These electrodes produce electrical impulses that regulate abnormal impulses. Or, the electrical impulses can affect certain cells and chemicals within the brain. The amount of stimulation in deep brain stimulation is controlled by a pacemaker-like device placed under the skin in your upper chest. A wire that travels under your skin connects this device to the electrodes in your brain.
Deep brain stimulation is used to treat a number of neurological conditions, such as:
- Essential tremor
- Parkinson's disease
Deep brain stimulation is also being studied as an experimental treatment for epilepsy, cluster headaches, Tourette syndrome, chronic pain and major depression. Many candidates for deep brain stimulation are participants in clinical trials.
- Deep brain stimulation for Parkinson's disease. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/deep_brain_stimulation/deep_brain_stimulation.htm. Accessed Oct. 13, 2012.
- Kluger BM, et al. Surgical treatment of movement disorders. Neurology Clinics. 2009;27:633.
- Brunicardi FC, ed., et al. Schwartz's Principles of Surgery. 9th ed. New York, N.Y.: The McGraw-Hill Companies; 2010. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=50. Accessed Oct. 11, 2012.
- Katz M, et al. Referring patients for deep brain stimulation. Archives of Neurology. 2011;68:1027.
- Ward HE, et al. Update on deep brain stimulation for neuropsychiatric disorders. Neurobiology of Disease. 2010;38:346.
- Magis D, et al. Neurostimulation therapies for primary headache disorders: present and future. Current Opinion in Neurology. 2012;25:269.
- Bronstein JM, et al. Deep brain stimulation for Parkinson disease. Archives of Neurology. 2011;68:165.
- Sankar T, et al. Novel applications of deep brain stimulation. Surgical Neurology International. 2012;3(suppl 1):S26.
- Deep brain stimulation. American Association of Neurological Surgeons. http://www.aans.org/Patient%20Information/Conditions%20and%20Treatments/Deep%20Brain%20Stimulation.aspx. Accessed Oct. 13, 2012.
- Klassen BT (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 13, 2012.